The RESTORE Transformation can be a powerful experience.

The RESTORE infusion program is the most rapidly effective and life-changing experience available today. A 3-Day revitalization program with RESTORE Infusion Therapy® can restore-reboot-revitalize your life. The RESTORE Infusion is the next generation of molecular neuromodulation therapy that works so quickly, often following the very first session, many of our patients almost immediately begin to feel brighter, happier and more relaxed.

Our remarkable 3-day RESTORE infusion program can lead to rapid change and dramatic improvement by quickly “restoring” your neurochemical balance and rapidly “rebooting” neural connections, allowing you to enjoy life again.  But more than that, it also rapidly reduces inflammation associated with chronic stress, depression and pain, while helping to restore immune and hormonal functions to normal. And the unique transformational experiences that are often encountered during the sessions provide you with the opportunity to appreciate a new, vital and expanded perspective of life.

We understand that living with chronic stress, depression, anxiety or chronic pain can be difficult, but considering RESTORE Infusion Therapy® is a step in the right direction.  And you're not alone, we have been there too and we understand what it's like.  We don't treat patients... we help people, one person at a time.


Join with our other patients who come to us from across the nation and internationally with some of the most difficult and complex illnesses imaginable. Many have suffered from severe depression, anxiety, and PTSD. Others have experienced severe chronic pain including migraines, fibromyalgia and neuropathy for years and have not found relief with standard medical or psychological treatment.

Our patients have often been labeled as “treatment-resistant” or have been told by well-meaning professionals to “learn to life with it” and offered little hope. But even in these extreme cases, the RESTORE  3-day revitalization infusion can lead to remarkable, life-changing transformations.


RESTORE  Ultra-Rapid Infusion Therapy is the only ketamine-based infusion program that can be completed in just 3 days and provide long-term relief of symptoms without the need for continued “maintenance” infusionsRESTORE is widely recognized as the most effective, longest lasting ketamine therapy available in the world. In only 3 days with 3 personalized/precision medicine treatments, up to 85% of patients with “treatment resistant” conditions including depression, migraines or chronic pain obtain relief and see dramatic, long-lasting improvement -  with RESTORE.

What Our Patients Are Saying About the RESTORE Infusion

"In August I was in the worst depression of my life, feeling as if it would never end….While researching ketamine infusion centers we came across Ketamine Research Institute. The doctor spent an hour on the phone with us and we had an appointment within the week. I had three infusions which literally in every sense of the word restored my life within a week.

It can only be explained by a miracle. I am now on the least amount of psychiatric medications I have been since I was 13 years old. I enjoy my life each and every day. Don’t get me wrong everyone has their ups and downs and I do, but I’m able to brush it off. I’ve been given the gift of being able to smile a real true smile again!

I feel like me, better than me. I feel like a huge weight has been lifted off my shoulders. I am going back to school to finish my master’s degree and my husband and I our relationship is just like it used to be.”

EP - New York, NY


The RESTORE Ultra-Rapid Infusions

restore ultra rapid infusion

RESTORE sets new standards for rapid and long-lasting relief and is customized to each person and provided with one-on-one dedicated care. It is faster acting, longer lasting and more effective than any other ketamine infusion and 6-8X more effective than the new esketamine nasal spray – Spravato.

When patients fail to improve after multiple regular ketamine infusions, they are often referred to us. Even in these extreme cases, the RESTORE Infusion is very effective because it is a precise and targeted therapy combined with an innovative treatment protocol that greatly improves its efficacy. In addition to metabolic optimization of each patient we see, the RESTORE infusion is a unique combination of ketamine and magnesium additives to make it more effective, that it is administered by a proprietary 3-stage variable rate infusion to provide the optimal blood levels needed for a longer period of time. That is why it is faster acting, more effective and longer lasting than a regular ketamine infusion and why RESTORE is considered the “Gold Standard” in ketamine-based infusions that all others are compared to.

Just compare the remarkable effectiveness of the RESTORE Ultra-Rapid Infusion in the treatment of major depression compared to standard antidepressant medications –

ketamine vs other treatments*2 or more antidepressants in combination and/or the addition of mood stabilizers or atypical antidepressants, with psychotherapy and/or ECT - Practice Guidelines for the Treatment of Psychiatric Disorders Compendium - American Psychiatric Association


Why are the RESTORE Ultra-Rapid Infusions So Effective?

It is becoming common knowledge that ketamine is the most effective and rapid treatment available for many disorders including depression, anxiety and PTSD.  Even the major drug companies, including Johnson & Johnson, Janssen and Allergan are stopping research into older antidepressants and rushing into the development of new drugs that they hope will come close to duplicating the rapid and remarkable benefits of the ketamine infusion.

There is little wonder why this is happening when you consider the dramatic improvements that can occur in just 24 hours after just a single infusion. There are no current medications or treatment that can match the seen with ketamine.

What About The New Nasal Spray - Esketamine?

While the pharmaceutical companies are trying to make something almost as good as ketamine, the results have been disappointing. Although Esketamine (Spravato), the new Janssen Pharmaceuticals nasal spray, has recently been FDA approved for the treatment of certain forms of depression, it has been found to be significantly less effective and much more expensive than a ketamine infusion and is also noted to produce more frequent and longer lasting adverse side effects.

Spravato appears to be a modest improvement over current conventional antidepressant medications, although it was only able to produce somewhat positive responses in 3 out of 5 FDA phase III trials.  In those studies, people who received intra-nasal esketamine improved slightly more than those that took a placebo (inactive spray).  A number of those patients also reported negative side effects that could last almost 2 hours after taking the nasal spray.  After all that research and development, esketamine may not be the "breakthrough" new treatment they were hoping for but it is a step in the right direction.

Is There Anything Even Better Than A Ketamine Infusion...Yes

Even the "standard" ketamine infusion, developed in 1994 and used by many private centers, universities and the National Institute of Mental Health is not nearly as effective or as long-lasting as it could be.  Nonetheless, ketamine infusion therapy is still widely regarded as the most effective treatment available for conditions such as depression, anxiety and PTSD. Research has shown that it is effective for over 70% of people who have not responded to conventional antidepressant therapy. Unfortunately, most health insurers regard it as an “investigational” therapy and do not cover the treatment.

While this treatment is becoming more available in the United States, most centers charge between $500-$600 per infusion. But it is important to remember that you will need 6 infusions over 12 days to obtain maximal improvement and then monthly “maintenance” infusion after that, so it can become costly.

We recognized that not everyone needs the RESTORE infusion, so in order to make this remarkable therapy more affordable and available to those that could benefit from it, we have instituted the first and only comprehensive Training Program for Physicians and other practitioners in the United States. Our program trains Psychiatrists, Anesthesiologists and other qualified practitioners interested in providing this therapy to patients. The course specifically trains physicians and practitioners to safely and effectively administer the standard ketamine infusion protocol developed at Yale in 1994-2000 and is currently used by the National Institute of Mental Health and other major institutions around the world.

In addition, we also offer the "standard" ketamine infusion at a reduced cost as an option to our patients who may not require the more advanced RESTORE Infusion
                    We provide the conventional  Yale-NIMH ketamine infusions for $350.00.

That being said, we know that a ketamine infusion could be even better!

We have taken a different approach...

As a former Assistant Professor in the Department of Anesthesiology of Yale School of Medicine where the ketamine infusion for depression was first developed in 1994, I have had many years of experience with ketamine and developed the RESTORE infusion to improve upon the basic ketamine infusion. Using RESTORE, we have successfully treated some of the most difficult cases that have not been helped with any other conventional, alternative medical therapy or even multiple regular ketamine infusions.

Rather than changing what we already know works well or being satisfied with the standard infusion…we unlocked the full potential of ketamine and made it even better and longer lasting!

restore is better

That is why RESTORE represents the new "gold standard" in ketamine infusion therapy. We are the only center in the United States that offers  the Yale-National Institute of Mental Health ketamine infusion, also known as the “standard ketamine infusion", as well as, the more effective, longer-lasting RESTORE Advanced Infusion and  RESTORE Essential Infusion.

Now you have choices....

Standard Ketamine Infusion

The RESTORE Infusion Therapy Difference

The RESTORE Ultra-Rapid Difference

Restore versus the Standard ketamine infusion

How Effective is RESTORE? – One Patient’s Experience

"Rock bottom and out of options is where I found myself in 2016. Suffering from 2 to 3 partial/myoclonic seizures per week, intractable migraines and severe clinical depression, had left me broken and struggling to find the will to keep going.

I went through years of the awful gauntlet of tests and prescription meds whose side effects were as horrible as my conditions and did nothing to relieve my symptoms. My quality of life, due to all my health issues, had slowly disappeared and with 4 amazing children to care for, all hope had left me.

Then one day I came across a report about Ketamine therapy on NPR radio and started researching and was quickly led to the Ketamine Institute and Restore. After having years of awful experiences with neurologists, I was absolutely blown away by their balance of professionalism and impeccable bedside manner after our initial phone call.

That first treatment gave me my life back! The entire experience is absolutely incredible. They truly focus on treating the whole patient and are there guiding every step of the way. Best decision of my life."

SK - Milwaukee, WI

See what our patients are saying about the RESTORE Ultra-Rapid Infusion

Read "Olive's View of Heaven"


That Is The RESTORE Infusion Therapy Difference

Learn how we developed the RESTORE Ultra-Rapid Infusion

So, Before You Decide….

chosse what is right for you

Having Options Is Important

Undertaking any form of new therapy or treatment for a serious medical condition can be a concern for you and your family. So, before you consider ketamine treatment with anyone, find an experienced and trained physician, ask a lot of questions and be satisfied with the answers.

Unlike other centers, I personally evaluate, select and treat each and every patient at the Ketamine Research Institute. I administer each RESTORE Ultra-Rapid Infusion  myself and only see one patient at a time, so you have my full attention throughout the entire process. We spend a great deal of time with our patients before, during and after all RESTORE infusion sessions. This is a comprehensive and specialized treatment, so we take the time that you need to obtain the best results.

Learn why not all ketamine infusions are the same

A Little About Us…

The Ketamine Research Institute was founded to continually improve and perfect ketamine treatment for an expanding range of chronic illnesses. We have spent many years working to enhance and expand the benefits of ketamine infusion therapy.  Much of our work was inspired by our desire to help relieve the pain and suffering of seriously injured soldiers returning from Iraq and Afghanistan with complex pain, depression and PTSD issues.

After devoting almost 2 decades to the clinical use, research and development of this innovative therapy, employing precision medicine and targeted therapy, we have developed the most advanced ketamine-based therapy available in the RESTORE Infusions.  We have improved on the original standard ketamine infusion, making the RESTORE Ultra-Rapid Infusion the most effective, efficient and longest lasting treatment available.

We are a very specialized center devoted exclusively to ketamine treatment and educating physicians in the use of ketamine. We focus solely on ketamine therapy to ensure that you have the best possible opportunity to improve with our infusions.

More than that, we are leading the way in the field of ketamine infusion therapy and physician education by establishing the first International Training Program for Physicians in Ketamine Infusion Therapy. Our hope is to bring this remarkable breakthrough therapy out of the research lab and into your physician's office.

Educating Physicians in Ketamine Infusion Therapy...

We Have Set The Standards…

We are all in this together and we understand what it's like

We are committed to what we do because we understand what it's like to deal with these issues.  So, we will use all our knowledge, experience, training and expertise to help you. And while we cannot promise success in every case, we can promise and guarantee, that we will make every effort and take every step necessary to ensure that you have the best possible chances of recovery.

Our location on the campus of Doctors Hospital of Sarasota enables us to provide you with an integrated healthcare environment offering a broad range of medical expertise and services immediately available. Cooperation among your physicians is a very important element when dealing with complex illnesses and we work closely with your physician and those on our campus to bring you the best possible care.

Our new location

Learn more about the RESTORE Infusion Therapy difference.

Time is precious. You want to feel better as fast as you can and we do too. The RESTORE Infusion program only takes 3 days; not 2 weeks like other infusion programs. Better yet, we offer weekend treatments, so you can begin on Friday and be home on Sunday. Why spend all of your time and money waiting for 2 weeks to feel better?

Call Us Today! 800.850.6979

RESTORE Infusion Center

Ketamine Research Institute - Sarasota, FL

OK, I'm Ready To Be Restored!...The RESTORE Ultra-Rapid Infusion


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