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Ketamine infusion options


Not All Ketamine Infusions Are The Same

Standard Ketamine Infusion or the Restore Ultra-Rapid Infusion

It may come as a surprise to find out that not all ketamine infusions are the same. Although people might say that ketamine is just ketamine, and that is generally true, there is a little more to it than that. Like anything else, depending upon how it is used, the effects can be altered very substantially.

Restore versus the Standard ketamine infusion

Realizing this, we have utilized it in many ways and through years of clinical use and research, developed different options to increase its remarkable benefits for your treatment that are unique. The Ketamine Research Institute is the only center in the United States that offers both the Yale-National Institute of Mental Health ketamine infusion, also known as the “standard” ketamine infusion, as well as the advanced and more effective Restore Ultra-Rapid Ketamine Infusion.  And soon....the new Restore Advanced Infusion.

Let’s look more closely at some of the differences between the two infusion options….

Standard Ketamine Infusion

Compared to

restore ultra rapid 3 days


Standard Ketamine Infusion


ketamine picture

Description:  

The ketamine infusion most commonly used today was originally developed at the Yale University School of Medicine  in 1994.  In 1999-2000 it was discovered to be rapidly effective for the treatment of mood disorders such as depression, anxiety and PTSD.  It  has since become known as the standard ketamine infusion and used by the National Institute of Mental Health, major universities and ketamine centers throughout the world.

standard ketamine infusion series


Currently Used To Treat:

Depression      Bipolar Illness      Anxiety      PTSD

Standard Ketamine Infusion – Basic. 6 Infusions/14 Days Series Includes -

The Standard Ketamine Infusion includes all aspects of care as recommended by the American Psychiatric Association and the American Society of Anesthesiologists, this includes:

Initial Evaluation:
Comprehensive Initial screening and assessment.
Review of medical records, depression, anxiety and pain metrics.
Review of all prior laboratory tests and evaluations.
Comprehensive treatment plan including consultation with each patient and family members regarding infusion protocol and infusion experience.

Standard Ketamine Infusion:
Standard ketamine infusion – Yale-National Institute of Mental Health Protocol
Infusion with consideration of your current medications and body weight.

Monitoring:
Physician supervised -
RN/Staff present with continual visual and vital signs monitoring including:
Heart rate
EKG
Blood pressure
Pulse Oximetry

Meets all recommendations:
American Psychiatric Association-
A Consensus Statement on the use of Ketamine in the Treatment of Mood Disorders
American Society of Anesthesiologists-
Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists

Re-assessments:
Staff - Post infusion assessment

Post-Infusion Maintenance Therapy:
Patient generally do best with regular maintenance infusions scheduled monthly.

Maintenance Therapy:

Requires continued regular maintenance infusions - usually on a monthly basis
Patient generally do best with regular maintenance infusions scheduled monthly. This maintains the benefits achieve during the initial therapy.  Of course, if something happens such as a very stressful life circumstance or traumatic event, then additional subsequent infusions may be needed more frequently for a short time.

Advantages:

Simple – Standard amount of medication based on body weight - may vary slightly on occasion.
Effective – 70% of patients' experience improvement in their symptoms.
Reduced Medication – Some patients may find they can reduce or discontinue prior medications that were not helpful.
More Common – Because the standard ketamine infusion is becoming more widely recognized as an effective treatment and more physicians are offering it, so it may be available near you.

Disadvantages:

The initial time commitment (two weeks) can be a barrier. Also, the benefits are often only temporary, so you may require ongoing treatment each month which can become expensive for many people. There is also the possibility that with repeated monthly exposure to ketamine, over time you may develop increasing tolerance or resistance to the drug and lose the benefits.

Note - The standard ketamine infusion may not be significantly or consistently effective for the treatment of migraines, painful neuropathy, fibromyalgia, RSD/CRPS or other types of neuropathic pain syndromes.

Cost:

Total cost for initial assessment and 6 infusions -14-day treatment series – $2950.00 USD
Maintenance infusions are $450.00


The Restore Ultra-Rapid Infusion is uniquely different and a major advancement in ketamine infusion therapy.  By combining Precision Medicine and Personalized Care Restore can bring more rapid relief symptoms in just 3 days and provide long term improvement.

Restore is the most effective infusion


Also, coming soon...

restore ultra rapid 3 days


Restore picture

Description:

The Restore Ultra-Rapid Infusion is the most effective, efficient and rapid infusion therapy available.  It was developed over 15 years of clinical research to effectively treat a wide variety of medical issues in the most efficient manner possible.

We discovered in 2002, that successful infusion therapy must be custom tailored to the individual and the specific medical condition to achieve the best effect.  To do that, we spent years of clinical research determining the most effective dose and method for each specific condition.  But more than that, we also knew that each person responds to medication differently.  Because of that, we carefully consider current medications, each person’s basic metabolism and genetic profile to optimize each infusion for that individual patient.

More than that, we also employ a specialized environment to enhance the effectiveness of our infusions that include proprietary synergist medications and protocols during each infusion session for maximal effectiveness.  These factors allow us to accomplish in just 3 sessions what others may not be able to achieve with 6 or more infusions.  Not only that, the benefits of feeling better last much, much longer than those seen with the basic ketamine infusion.

restore is better


Currently Used To Treat:

Mood Disorders:                         Chronic Pain:                         Has Been Helpful in:
Depression                                    Fibromyalgia                          IBS - Irritable Bowel Syndrome
Bipolar Illness                               Migraine Headaches            CFIDS - Chronic fatigue Syndrome
Anxiety                                           Neuropathy                            RLS - Restless leg Syndrome
PTSD                                              RSD/CRPS                             Pelvic Pain - Vulvodynia - Pudendal Neuralgia

Restore Ultra-Rapid 3-day Intensive Infusion Series Includes -

Initial Evaluation:
Comprehensive Initial screening and assessment:
Review of medical records, depression, anxiety and pain metrics.
Review of all prior laboratory tests and evaluations.

Also includes -
Review and optimization of critical metabolic issues including thyroid hormone levels, testosterone/estrogen levels, Vitamin D, B6 and B12 levels as necessary. Additional testing for acetyl-L-carnitine or ALCAR may also be recommended.
May also include Genecept Cytochrome P450 analysis and BDNF variant screen.
Comprehensive treatment plan including extensive consultation with each patient and family members regarding infusion protocol and infusion experience.

Infusion Series:
Restore Ultra-Rapid three-part sequential enhanced and optimized infusion

Each infusion is optimized to each patient's individual physiological and psychological response based upon pharmacokenetic parameters.

Also includes - 
Pre-Infusion analysis:
Genomic Profile: Infusion optimization per genetic profile, current medications, sex, and adjusted body composition and prior treatment history.
Pharmacokinetic Optimization: Each infusion is optimized based on computer modeling of blood level concentrations.
Pharmacodynamic Monitoring: Each infusion is continually monitored and adjusted based upon psychological and physiological response.
Synergistic Agents: Synergistic medications used as indicated to increase the effectiveness and durability of basic ketamine.

Monitoring:
Physician always present with each patient:
Continual real-time monitoring, including
Heart rate and heart rate variability
EKG
Blood pressure
Pulse Oximetry

Also includes -
Proprietary Optimization Protocol:
Restore Adjuvant administration
Autonomic nervous system monitoring and assessment
Pharmacokinetic monitoring
Reassessment of pharmacokinetic profile and response
Continual, minute-to-minute infusion adjustments and modifications.
Intra-infusion cognitive reframing and enhancement.
Acoustic and visual modification and entrainment.
May also include EEG alpha/theta suppression surveillance rates/data adjustment.

Meets and exceeds recommendations:
American Psychiatric Association-
A Consensus Statement on the use of Ketamine in the Treatment of Mood Disorders
American Society of Anesthesiologists-
Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists

Re-assessments:
Post infusion assessment by attending physician

Also includes - 
Review of physiological and psychological response
Review of pharmacokinetic and Pharmacodynamic response
Spatial and Chromatic analysis of subjective infusion experience
Inter-Infusion re-evaluations and reassessments by physician.

Post Infusion Maintenance:
Restore supplement oral suspension – enhances effectiveness and prolongs durations of improvements

Maintenance Therapy:

The fewest maintenance infusions are needed –
After the first 3 infusions, patients' generally require only 2-3 maintenance infusions. After that, the beneficial changes become even longer lasting and fewer if any infusions are needed. Of course, if something happens such as a very stressful life circumstance or traumatic event, then subsequent infusion may be needed for a short time.

Advantages:

Very Effective – 85% of patients’ experience improvement in their symptoms
Very Rapid – Only requires 3 infusions, given over 3 days to complete
Longer Lasting – Improvements last for months to years, no need for frequent maintenance infusions
More ComprehensiveRestore Ultra-Rapid Infusion is effective for many more conditions than the standard infusion
Cost Effective – Initial Series and maintenance infusions cost less over the first year of treatment than any other option.
Time Effective –Less time away from home and work
Reduced Medication – Most patients find they can reduce or discontinue prior medications that were not helpful.

Disadvantages:

Only available at the Ketamine Institute in Sarasota, FL at the present time.

Cost:

The total cost of the Restore Ultra-Rapid Infusion treatment is $4950.00 USD
Once the initial therapy is completed and each person’s optimal response level is determined, the cost of the maintenance infusions is only $825.00.


Also, coming soon - Restore Advanced Infusion

That is the Restore Ultra-Rapid Infusion difference.


 

“The most important breakthrough in antidepressant treatment in decades”....

Thomas Insel, MD - Director, National Institute of Mental Health



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