To us, it's all about finding your own path....

American physicist Joseph Henry once noted:

"The seeds of great discoveries are constantly floating around us, but they only take root in minds well prepared to receive them."

RESTORE Infusion...The "Gold Standard"
in Ketamine-Based Therapy

Anything worthwhile takes time...

RESTORE results from over 35 years of my clinical research and experience using ketamine, personally administering ketamine-based therapy, to treat a wide variety of complex and challenging medical issues to patients who have come to us from around the world seeking help.

I formulated the RESTORE Infusion protocol to improve and optimize the standard ketamine infusion that was developed at my former institution - the Yale Department of Anesthesiology - in 1994. The goal was to make ketamine-based infusion therapy as rapid, effective, and long-lasting as possible.

Over the years of my work with ketamine, I have gained more direct "hands-on" clinical experience providing ketamine infusion therapy than any other physician in the United States.  The knowledge, experience, and insights gained by personally guiding hundreds of patients through thousands of ketamine infusions have been invaluable in learning how to unlock the therapeutic potential of ketamine.

After devoting over three decades to the clinical use, research, and development of this innovative therapy — employing metabolic optimization, precision medicine, and targeted infusion therapy — I have developed the most advanced ketamine-based treatment available in the RESTORE Infusion.

Today, the RESTORE infusion® is regarded as the "gold standard" in ketamine-based treatment


Learn more about the inventor of the RESTORE Infusion


About Us

We are committed to what we do, and we focus on just one thing - ketamine-based therapy. We promise to use all of our knowledge, experience, and expertise to provide each person we meet with the best possible treatment available for the relief of their illness.

We are working every day to help individuals who are suffering from complicated and treatment-resistant disorders that have been given up on by other healthcare providers. It can be difficult, and it takes time, effort, and experience working with one person at a time to get the greatest possible result.

We also continue to explore new applications for the therapeutic potential of ketamine in other illnesses, such as neurodegenerative diseases, autoimmune and inflammatory disorders - extending the possible benefits of ketamine therapy to many more people for illnesses that have previously been difficult to treat with conventional approaches.

More than anything, we want this cutting-edge therapy to be more readily accessible and affordable to those who could benefit from it, so we educate other doctors and medical practitioners on how to use and administer the most evidence-based, safe, and effective form of ketamine treatment to their own patients.

The Ketamine Research Institute was founded to continually improve and perfect ketamine treatment for an expanding range of chronic illnesses. We have improved the original standard ketamine infusion with the RESTORE Ultra-Rapid Infusions® - the most effective, efficient, and longest-lasting treatment in the world. After devoting almost two decades to the clinical use, research, and development of this innovative therapy and by employing precision medicine and targeted therapy, we have developed the most advanced ketamine-based treatment available in the RESTORE Infusions®.

In addition to the metabolic and genetic optimization of each patient we see, the RESTORE infusion process is a unique combination of ketamine and magnesium, making it more effective.  Our highly trained medical specialists then administer our infusion using a proprietary 3-stage variable rate infusion protocol to provide optimal blood levels for a more extended time. That is why RESTORE is faster-acting, more effective, and longer-lasting than any other regular ketamine infusion. And the beneficial results can begin in just minutes to hours after the first infusion.

We are a very specialized center devoted exclusively to ketamine treatment, clinical research, education, and training physicians worldwide in the use of ketamine. We have developed the first and most comprehensive educational training program for clinicians using Ketamine Infusion Therapy for Mood Disorders.  More than that, we have established an international multidisciplinary collaboration initiative with centers in Australia and Europe to share knowledge and expertise with physicians on the cutting-edge of ketamine therapy.  Also, to ensure that all ketamine centers provide treatment most effectively and safely, the Ketamine Research Institute has developed the first International Standards for Ketamine Infusion Centers in collaboration with our partners.  Our goal is to ensure that you have the best possible opportunity to improve with ketamine infusion therapy.

Our Training Program...

Setting the Standards...

A Little History About Ketamine...

The original ketamine infusion for the treatment of depression was first discovered in 2000 at the Yale University School of Medicine by Robert Berman, MD, and others.  The Department of Anesthesiology assisted in formulating and administering the very first infusion protocol of "0.5 mg/kg given over 40 minutes" in 1994. This original protocol has since become the "standard" ketamine infusion and is currently used by many others worldwide as a rapid treatment for depression and other conditions.

I was also very involved in the early days of ketamine treatment, using it to help patients find relief from chronic pain. Even before that, as far back as the mid-1990s, I utilized this amazing medication to treat pain and later used it extensively at the Mount Sinai Medical Center in New York City before our work at Yale. Those of us with previous ketamine infusion experience knew that it was remarkably effective for depression and pain and for treating many related disorders. The problem was that no one knew the most effective dose or formulation of ketamine for any individual patient. Secondly, the very rapid beneficial effects only lasted a few days. Well, that was certainly a good start, but I knew it could be better, and that realization and understanding led to the development of RESTORE.

Standard versus Restore

The Ketamine Research Institute was founded to expand and perfect ketamine infusion therapy. I have spent years improving on the original "standard" ketamine infusion protocol, treating hundreds of patients with some of the most severe and complex pain, depression and anxiety disorders imaginable. Now we have been able to solve many of the issues that faced us before with  the RESTORE Ultra-Rapid Infusions - Essential and Advanced

the "Gold-Standard" in ketamine therapy

Learn why RESTORE is better than ketamine



We Put The Pieces Together

Today, through our use of Precision Medicine and  exploration of allied fields in medicine, neuroscience, pharmacogenomics and cognitive science, we have discovered and pioneered synergistic ways to enhance its effectiveness and extend the duration of the RESTORE Ultra-Rapid Infusion beyond anything currently reported in the medical literature.

Our research and development efforts have unlocked the keys to the most effective, rapid and long lasting treatment of pain and depression available today.  This unique and proprietary ketamine based infusion protocol known as RESTORE represents the next generation of clinically proven rapid, effective, long-lasting and safe ketamine based infusion treatment.

Learn why not all ketamine infusions are the same


Through our expanding research efforts to explore its broader application, RESTORE is also be the first medication/protocol of its kind to relieve symptoms of Fibromyalgia, Neuropathy, PTSD, migraine headache, as well as, many other serious conditions such as pelvic pain-vulvodynia-pudendal neuralgia.



We Work As A Team

This is a team effort and requires expertise from many related fields. To ensure our patients comprehensive care, the Ketamine Research Institute and our trained and certified practitioners collaborate on an ongoing basis sharing knowledge and expertise in this rapidly expanding field. We network to share the latest developments in the field, answer questions and build a shared database to conduct clinical research into ketamine-based therapy.

Chronic pain and mood disorders represent an immense clinical problem. With tens of millions of people in the United States alone suffering from the burden of these debilitating illnesses, there is a moral obligation to reduce this burden by improving the understanding and treatment mechanisms, developing new therapies, optimizing and testing existing therapies, and improving access to evidence-based care.


We bring together a multidisciplinary international collaboration in the field of ketamine-based therapy, bringing together scientists, clinicians, healthcare providers, and policy makers to stimulate and support the study of ketamine and to translate that knowledge into improved relief worldwide.


The Ketamine Research Institute is the only center in the United States that provides...RESTORE - the "Gold Standard"

We are proud to be the only center in the United States dedicated solely to the advancement of RESTORE Infusion Therapy. We provide education to other physicians in its use and bring the latest breakthrough discoveries about ketamine out of the research lab and into our infusion centers to help the people who need it most today.

Learn more about the RESTORE Infusion Center here >

 Tag Line RRR

What patients are saying about the RESTORE Infusion

Now You Know About Us.....Call And Tell Us About You!