Ketamine Research Institute Training Program

"The Ketamine Research Institute's Advanced Ketamine Training for Experienced Clinicians is an extraordinary opportunity for those seeking to advance their knowledge and skills in ketamine infusion therapy. Our 2-day intensive program takes you beyond the basics, providing an unparalleled educational experience that is both comprehensive and evidence-based.

Our program is designed to exceed all training recommendations set forth by the APA and ASA, ensuring that our participants receive the highest standard of training available. Our "hands-on" clinical experience and individualized training allow you to learn from experienced professionals and apply your knowledge in real-world settings. We believe that our program is the best available, and we invite you to join us in advancing the field of ketamine therapy"...

GW Grass, MD — Ketamine Research Institute

Transform Your Ketamine Infusion Practice: Master Precision Medicine and Advanced Targeted InfusionTechniques 

This is an Advanced Ketamine Infusion Course Designed for Clinicians with Prior Experience who Wish to Take Ketamine Therapy to the Next Level

Are you a clinician offering ketamine infusion therapy in your practice but experiencing less than optimal patient outcomes and therapeutic response rates? Discover how advanced and comprehensive ketamine training with the Ketamine Research Institute (KIT) can elevate your practice and significantly improve patient results.

Our Advanced Ketamine Infusion Training program is designed to elevate your practice to new heights by providing in-depth knowledge, hands-on experience, and cutting-edge techniques that cater to the unique needs of your patients. By undertaking this comprehensive training, you can revolutionize your ketamine practice and offer unparalleled care to those seeking relief from mood disorders and chronic pain.

Embrace the Importance of Advanced Ketamine Training for Optimal Outcomes

As a skilled medical professional, you already know that the success of ketamine infusion therapy depends on various factors. However, you might not be aware of the critical role that advanced and comprehensive training plays in optimizing treatment outcomes. KRI's advanced training program delves deep into these essential aspects, ensuring you're equipped to tackle any challenge and provide the highest quality care.

Comprehensive Understanding of Ketamine Therapy

Mastering the complexities of ketamine therapy involves developing a thorough understanding of various elements that contribute to its success. KIT's advanced training program covers the following:

Understanding Ketamine Pharmacokinetics and Pharmacodynamics for Optimal Patient Outcomes

Ketamine is a powerful medication that has shown promising results in treating various mood disorders and chronic pain conditions. However, its effectiveness largely depends on healthcare providers' understanding of the complexities of ketamine's pharmacokinetics and pharmacodynamics. This knowledge is critical for achieving optimal patient outcomes.

Pharmacokinetics: Ensuring Proper Absorption, Distribution, and Elimination

Pharmacokinetics involves the study of how a drug is absorbed, distributed, metabolized, and eliminated by the body. A deep understanding of ketamine's pharmacokinetics allows providers to:

Determine appropriate dosages: Administering the correct dosage based on a patient's individual factors, such as age, weight, and medical history, is essential for ensuring the drug's efficacy and minimizing the risk of side effects.
Manage drug interactions: Understanding how ketamine interacts with other medications can help providers identify potential drug interactions that can impact ketamine's effectiveness or lead to adverse effects.
Optimize infusion rates and concentrations: Adjusting infusion rates and therapeutic plasma concentrations based on a patient's response to the treatment can help manage side effects and improve patient comfort during the infusion process.

Pharmacodynamics: Unraveling the Mechanisms of Action

Pharmacodynamics focuses on studying how a drug interacts with its target receptors and produces its therapeutic effects. Gaining a comprehensive understanding of ketamine's pharmacodynamics is crucial for the following:

Tailoring treatment to individual needs: Recognizing how ketamine interacts with different receptor types, such as NMDA and AMPA receptors, can help providers customize treatment protocols to suit each patient's unique genetic makeup and response to the medication.
Maximizing therapeutic effects: Understanding the mechanisms through which ketamine exerts its antidepressant and analgesic effects can help providers optimize treatment regimens to achieve the best possible patient outcomes.
Addressing metabolic or genetic variations: Knowledge of how genetic variations in factors like the MTHFR gene or BDNF production can impact ketamine's effectiveness allows providers to make necessary adjustments to treatment plans, ensuring that each patient receives the most effective and appropriate care for their specific needs.

A thorough understanding of ketamine's pharmacokinetics and pharmacodynamics is essential for healthcare providers to optimize patient outcomes. By mastering these complex aspects of ketamine therapy, providers can deliver personalized, effective treatment plans that maximize therapeutic benefits and minimize potential risks, ultimately improving the lives of patients struggling with mood disorders and chronic pain.

Precision Medicine and Target-Controlled Infusion Methodology: Key Components for Optimal Patient Outcomes

In the realm of ketamine therapy, precision medicine and target-controlled infusion (TCI) methodology are critical factors that contribute to achieving optimal patient outcomes. These approaches allow healthcare providers to tailor treatment protocols according to each patient's unique needs, ensuring patients receive the most effective and safe care possible.

Precision Medicine: Personalizing Treatment for Maximum Efficacy

Precision medicine refers to customizing healthcare interventions based on an individual's unique genetic, environmental, and lifestyle factors. In the context of ketamine therapy, implementing precision medicine can help providers achieve superior patient outcomes by:

Identifying genetic variations: Understanding how genetic variations, such as those in the MTHFR gene or BDNF production, can impact ketamine's effectiveness is essential for personalizing treatment plans. Providers can adjust the dosage, infusion rates, or treatment frequency to ensure optimal therapeutic effects.
Accounting for individual differences: Considering factors like age, weight, medical history, and concurrent medications can help providers tailor treatment protocols to each patient's specific needs, enhancing the therapy's effectiveness and minimizing the risk of adverse effects.
Incorporating adjunct therapies: Integrating additional treatments, such as adjunctive and synergist agents, nutraceuticals, and other complementary interventions, can further improve ketamine therapy's long-term effectiveness and help patients maintain the gains achieved during treatment.

Target-Controlled Infusion Methodology: Ensuring Safety and Comfort

Target-controlled infusion (TCI) is a technique that allows providers to deliver a precise and consistent amount of ketamine to patients throughout the infusion process. TCI is crucial for achieving optimal patient outcomes because it:

Minimizes the risk of side effects: By administering ketamine at a carefully controlled rate, TCI helps reduce the likelihood of adverse effects, such as significant changes in blood pressure, heart rate, or oxygen saturation levels. This approach ensures patient safety and comfort during the infusion process.
Allows for real-time adjustments: TCI enables providers to monitor and adjust the infusion rate based on a patient's response to the treatment, ensuring that the optimal drug concentration is maintained throughout the therapy session. This adaptability can help providers manage side effects and tailor the treatment to suit each patient's unique needs.
Enhances patient experience: By providing a more comfortable and controlled treatment experience, TCI can help patients feel more at ease during ketamine infusions, potentially improving the therapy's overall effectiveness.

Understanding and implementing precision medicine and target-controlled infusion methodology is critical for achieving optimal patient outcomes in ketamine therapy. By personalizing treatment protocols and ensuring safe and comfortable treatment experiences, healthcare providers can maximize the therapeutic benefits of ketamine, helping patients struggling with mood disorders and chronic pain achieve lasting relief from their symptoms.

In-Depth Knowledge and Expertise

The program dives deep into the complexities of ketamine pharmacokinetics and pharmacodynamics, ensuring you fully understand this powerful therapy's intricacies. With this advanced knowledge, you'll be better equipped to optimize treatment outcomes and provide personalized care based on each patient's genetic makeup and metabolic profile.

Redefining Ketamine Infusion Therapy: Master Precision Medicine and Innovative Ketamine Administration

The Ketamine Research Institute's Advanced Ketamine Infusion Training Program course aims to equip clinicians with the knowledge and skills to administer KIT more effectively and safely.

The program is led by Dr. Gerald W. Grass, a nationally recognized expert in ketamine therapy, who has been instructing physicians, fellows, and government organizations such as the Veterans Administration and the Department of Defense in ketamine therapy since 2013.

Meeting and Exceeding APA and ASA Guidelines for Ketamine Therapy Training

The Advanced KIT intensive training course is tailored to meet or exceed the recommendations for clinician training in ketamine infusion therapy by leading medical organizations such as the American Psychiatric Association (APA) and the American Society of Anesthesiologists (ASA). This commitment to rigorous standards underscores the institute's dedication to providing the highest education and training for clinicians seeking to incorporate ketamine therapy into their practices.

A Comprehensive Educational Experience with Evidence-Based Didactic Lectures and Hands-On Clinical Experiences

The comprehensive educational experience includes evidence-based didactic lectures, interactive discussions, case studies, and hands-on clinical experiences administering ketamine infusions. What sets this program apart from other ketamine infusion training programs is that it takes place at a fully operational ketamine center. In addition, it provides trainees with supervised "hands-on" clinical infusion experience under the guidance of more experienced clinicians, allowing them to experience a ketamine infusion personally.

Applications are Now Open for the Advanced Intensive Training Course.

Applications for the  Advance KIT training will be available shortly. For more information or to apply, interested individuals can visit the Ketamine Research Institute's website at

The Ketamine Research Institute's Advanced Ketamine Infusion Training for Experienced Clinicians program is an unparalleled opportunity for clinicians seeking to improve and transform ketamine infusion therapy effectiveness and patient satisfaction. With its comprehensive curriculum, personalized learning, and practical experience, the program provides participants with the skills and knowledge they need to administer ketamine safely and effectively.

Boost your Practice and Your Reputation

Completing an advanced ketamine training course demonstrates your commitment to providing the highest quality care to your patients. This accomplishment can enhance your practice's reputation and attract new patients seeking expert care.

Investing in an advanced ketamine training course can profoundly impact your practice, helping you provide exceptional care and achieve optimal patient outcomes. By continuously enhancing your knowledge and skills in this rapidly evolving field, you'll be well-equipped to offer cutting-edge, personalized treatments to those struggling with mood disorders and chronic pain.

To Learn More About Ketamine Training

Ketamine Research InstituteThe Ketamine Research Institute  is the only training program that offers an intensive, didactic, and experiential course in ketamine-based therapy. This is not a simple online course but an opportunity for clinicians to come and spend several days with us in an immersive learning environment - an actual ketamine therapy center. This type of training is undoubtedly more intensive and expensive, but the education, experience, ongoing support, and mentorship you receive are invaluable. Experienced experts in clinical ketamine research and therapy designed our programs. It incorporates the latest advances in our understanding of how ketamine works and new protocols and techniques to enhance ketamine effectiveness in a "real-world" setting that is not available anywhere else in the United States.


The Programs We Offer

Whether you are a psychiatrist, anesthesiologist, internist/family medicine specialist, nurse practitioner, or physician assistant, we have a program designed specifically for you. We offer the most comprehensive ketamine training program in the United States, complete with a Precision Medicine/TCI-based approach to ketamine therapy, clinical experience, and ongoing support required to become highly proficient in this cutting-edge treatment.

Our training program offers a variety of courses that can cater to all levels of experience with ketamine. From comprehensive introductory courses to more advanced specialized training, we provide the information and clinical experience necessary to safely and proficiently administer ketamine therapy. Our Precision Medicine-based approach ensures that each clinician understands how to individualize care for each patient. Additionally, our team provides ongoing support and resources to help clinicians stay up-to-date on the latest research and developments in ketamine therapy.

If you are a clinician interested in offering ketamine therapy, be sure to do your homework and only consider training programs that are reputable and offer comprehensive instruction. It could be the difference between success and failure in providing this potentially life-changing treatment to your patients.

We are confident that no other training program in the United States can provide the level of depth, clinical experience, and sophistication required to become a highly skilled provider of ketamine therapy than the Ketamine Research Institute.


What Our Graduates Are Saying

The “Ketamine Infusion Therapy for Mood Disorders” training course for clinicians went above and beyond my expectations. Dr. Grass' brilliance and profound professional expertise made this course an unforgettable and truly eye-opening experience. I can now understand Ketamine from a pharmacological, anesthesiology, psychiatric, medico-legal, and therapeutic perspective. I was able to put the contents I learned immediately into practice and my patients are already profiting from the knowledge I gained.

Ricardo Febres Landauro, MD - Neurologist/Psychiatrist

This is just a token of appreciation for your time and patience. When I enrolled in your program, it was not my intent to participate by exhaustively asking questions, but it became apparent that I had overestimated my fund of knowledge.

Although I have extensive clinical experience with ketamine, and I work at expanding my understanding of the fundamental physiology and pharmacology involved in the administration of ketamine for mental health disorders, I had no idea how much I didn't know.

All the knowledge that I had acquired needed the perspective and clinical understanding that you were willing to share. Thanks again for your help.

Your program exceeded all expectations"

Mark Garwin, MD - Anesthesiologist

"Thank you again for an informative, enlightening, and practical course! Christy and I thoroughly enjoyed our experience with you, and we are excited to get all of our ducks in a row to get started with the ketamine infusions for mood disorders.

We appreciate your offer to send your forms/documents in a pdf as this will give us a great start in providing the right documentation, consent, etc… which interestingly our malpractice carrier is requesting. (I guess PA is not as progressive as FL.)

The course was fantastic….exactly what I was hoping for….evidence-based, scientifically yet practically oriented…allowing us to not only understand the basics of these treatments but some insights as to improve our successes and minimize the “failures” through careful patient selection and optimization.

I am looking forward to applying what we have learned to improve the lives of those in our community who qualify for this treatment and approach! We again thank you for the opportunity and look forward to staying in touch!"

Theresa Burick, MD - Integrative Medicine Specialist

"The course was absolutely helpful! I needed this information to know how to start. Now I know what I need to obtain. However, I may still approach you when I have my first actual patient scheduled later this year and I would love some peer support from you and the others.

I felt I needed the hands-on information to be able to know what my clinic should be like, and now I have a lot of ideas. Also, I needed the scientific approach of how to calculate/know what plasma concentration can work for whom and how to possibly change it. Now I have something better I can work with than the Yale protocol as an IM or trochee dose (never seemed optimal and nobody explains it - yet people do whatever).

As I am not a psychiatrist or anesthesiologist I knew I had to do this training to cover my ass and I am grateful I did. I believe everyone working with Ketamine should experiment with it and other psychedelics. Nevertheless, you have to experience it to be able to serve others appropriately. Thanks for offering access to a personal experience, even for those who would not consider it otherwise."

Rixt Luikenaar, MD - OB/GYN, Transgender Specialist

"The course was Fantastic. Thorough without drawing in details. Fluid and open to conversation. Extremely helpful and exactly what I was looking for! I now have a massive head start in helping the people in my community.

The course surpassed all my expectations. It was all good and encompassing. I think your style which allows for conversation toward what the participants find useful or of interest works really well. And having the day-to-day forms, infusions notes, and protocol/SOP forms are just so exceedingly helpful.

About the "ketamine experience"... for me personally I would like to try it again to get the larger experience! Unfortunately for you, I only trust you to do it.  To see the differences between the way people respond to the experience really brought it home.

It was Excellent!"

Edward Campbell, MD - Anesthesiologist

"I thoroughly enjoyed the course and thought it was a good mix of science and practical knowledge. And of course, it was very helpful as I had no clinical experience with Ketamine and just a little knowledge from what I’ve read...

It gave me a clear road map moving forward. I’m sure there is a lot still to learn, but you never know what you don’t know until it arises....Having access to your forms and waivers, etc. is huge!...

No other training offers an actual infusion for us to experience what it’s like. Having done it now, I can appreciate how difficult it would be to explain it without having done it."

David Smith, MD - Internist/Family Practice

The Ketamine Research Institute

Our goal is to train the Top 100 Ketamine Clinicians in the United States. Our graduates will become leaders in their field, highly respected ketamine experts, and serve as a professional examples of clinicians providing the safest and most effective ketamine therapy available. The Ketamine Institute is leading the way in the field of ketamine infusion therapy and physician education with our new ketamine infusion training program.

We’re on a mission to accelerate the health care revolution. We have pioneered ketamine infusion therapy to bring the latest breakthrough discoveries about Precision Medicine and Target-Controlled Ketamine Infusions out of the research lab and into our infusion centers and educational programs.


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