Ketamine Research Institute Training Program

2023 "Mini-Fellowship" Intensive Ketamine Infusion Training for Clinicians — How the Ketamine Research Institute Educational Curriculum Complies with APA and ASA Recommendations

Ketamine Research Institute Training Program
Complies with APA and ASA Recommendations

Ketamine is a potentially effective treatment for mood disorders, including major depressive disorder (MDD). However, its long-term effects and potential for abuse are not fully understood, which makes its use in treating mood disorders controversial. Thus, comprehensive training for clinicians administering ketamine for MDD and other mood disorder treatments is crucial. To ensure safe and effective care, the American Psychiatric Association (APA) and the American Society of Anesthesiologists (ASA) have provided guidelines on clinician training in ketamine therapy, emphasizing the importance of proper training, ongoing education, a collaboration between healthcare providers.

APA and ASA Recommendations

The American Psychiatric Association (APA) and the American Society of Anesthesiologists (ASA) have released recommendations on clinician training in ketamine therapy. These guidelines provide a framework for understanding the potential benefits and risks associated with ketamine and best practices for administering it safely. With these resources, professionals can ensure that they provide quality care while minimizing potential harm from its use.

The recommendations outline the importance of proper training for didactic and supervised clinical experience to ensure clinicians provide safe and effective care. The guidelines also emphasize the need for ongoing education and collaboration between healthcare providers. Additionally, they recommend that all providers involved in administering ketamine therapy should be knowledgeable about its pharmacology, potential side effects, and contraindications.

The recommendations also emphasize the need for appropriate patient selection and review of the patient's medical and mental health records before consideration of ketamine-based therapy. Finally, it outlines the need for informed consent, alternative treatment options, and ongoing patient follow-up and monitoring to assess the long-term safety and efficacy of ketamine treatment for mood disorders. Finally, they outline the need for informed consent and other ethical considerations.

It is important to note that the guidelines provided by the APA and ASA are only recommendations. Clinicians should consult with their local governing bodies and state medical boards for specific rules and regulations regarding ketamine therapy in their area. Additionally, it is essential to review any additional literature on ketamine that may provide further insight into its use. By following these guidelines and taking the time to understand the potential risks and benefits, clinicians can provide safe and effective care for those suffering from mental health disorders.

The Ketamine Research Institute Training Program

The Ketamine Research Institute training program - "Mini-Fellowship" Intensive Ketamine Infusion Training for Clinicians, strives to meet or exceed all APA and ASA recommendations. Our intensive education course systematically reviews every essential aspect of ketamine therapy while ensuring compliance with APA and ASA standards.

The Curriculum and Learning Environment

The course is conducted in person and in an actual infusion center environment to facilitate learning and clinical experience. It includes comprehensive evidenced-based didactic lectures, case studies, and hands-on training to ensure clinicians are adequately prepared to administer ketamine safely and effectively—the hands-on training includes simulated scenarios to allow for practice in a controlled environment. This will enable clinicians to learn proper techniques for administering ketamine infusions safely and effectively.

Patient Selection, Dosing, and Administration

The curriculum covers the appropriate patient selection, dosing, and administration of ketamine, as well as the necessary patient monitoring and safety measures that should be taken during and after treatment, following APA and ASA recommendations.

At the core of any successful ketamine therapy program are rigorous patient selection techniques designed to select the best candidate for ketamine therapy and exclude those who may be unsuitable for treatment. Careful evaluation of a patient's psychiatric history, medical history, current medications, and metabolic profile provides valuable information to the ketamine clinician. This helps ensure that ketamine therapy is offered effectively with minimal risk to the patient.

In addition to careful selection, ketamine providers must be mindful of the patient's mood disorder diagnosis when developing an individualized ketamine therapy plan. Our training program emphasizes the importance of individualized treatment plans for each patient and the need for ongoing evaluation of treatment efficacy and potential adverse effects. Additionally, it stresses the importance of ethical considerations and the need for informed consent from patients considering ketamine treatment.

Below is a brief example of topics covered in the course related to APA recommendations.

An Example of APA Compliance:

Overview of mood disorders and the use of ketamine as a treatment option
Proper dosing and administration of ketamine
Patient monitoring and safety measures during and after treatment
Potential adverse effects and side effects of ketamine treatment
Patient selection and evaluation for ketamine treatment
Alternative treatment options for mood disorders
Current research on the long-term effects of ketamine use
Proper documentation, communication, and collaboration with other healthcare providers
Legal and regulatory considerations in ketamine treatment
Risks of off-label use of ketamine
Use of ketamine in special populations
Ongoing patient follow-up and monitoring
Ethical considerations in ketamine treatment
Practical training sessions
A multidisciplinary approach to ketamine treatment
Opportunities for continuing education and professional development.

Evidence-Based Didactics

Clinicians need to receive evidence-based didactics to provide safe and effective treatments with ketamine infusion therapy. This includes understanding the pharmacologic mechanisms of action of ketamine, identifying potential adverse effects, and correctly dosing and infusing ketamine.

Our comprehensive education program delves deeply into the evidence that supports ketamine infusion therapy regarding patient selection, dosing and administration techniques, vital sign monitoring during treatment, and post-treatment follow-up. Awareness of the science behind ketamine infusion therapy allows clinicians to provide safe and effective patient care.

Pharmacology - The Pharmacokinetic and Pharmacodynamics of Ketamine

In addition to providing a comprehensive understanding of ketamine treatment for MDD, the educational curriculum also covers essential topics related to pharmacology and pharmacokinetics. Clinicians will gain an understanding of the mechanisms of action of ketamine, its pharmacodynamic properties, and drug-drug interactions that must be taken into account when prescribing it. Furthermore, they will gain an understanding of the pharmacokinetic properties, including onset and duration of action, metabolism, elimination, and potential for abuse. Finally, they will learn about the factors influencing ketamine's efficacy, such as patient characteristics and comorbid conditions. Medical professionals need to understand this complexity to select the appropriate dose and frequency of infusion for each patient.

For example, a person with the CYP450 3A4 gene variant may experience extreme variations in maximum plasma concentration during a ketamine infusion. This could result in adverse effects or not obtaining any therapeutic benefit from the treatment. Without understanding the pharmacokinetics and pharmacodynamics of ketamine and how it is affected by genetic factors, medical professionals may be unable to provide optimal care to their patients.

Informed Consent

The course provides guidance on obtaining informed consent from patients before starting ketamine treatment. This includes advising patients of the potential risks and benefits of treatment and the alternative treatment options available. Clinicians should also explain the potential for dissociative symptoms and hallucinations associated with ketamine use.

Additionally, ethical considerations are essential when considering ketamine treatment due to the potential risks and benefits associated with its use. The need for patient autonomy and respect when making decisions about the course of treatment is also included. Finally, the need for ongoing follow-up, monitoring, and evaluation of treatment outcomes is emphasized.

Legal and Regulatory Aspects

The training program covers the legal and regulatory aspects of ketamine treatment, including the appropriate adherence to DEA and federal laws and regulations. Additionally, it provides training on the proper documentation of ketamine treatment in medical records and the importance of appropriate communication and collaboration with other healthcare providers involved in a patient's care.

Treatment Efficacy and Adverse Effects

Moreover, the training program covers the potential adverse effects and side effects associated with ketamine use, including dissociative symptoms, hallucinations, and potential for abuse. The importance of careful patient selection and evaluation is emphasized, including the need to screen for any contraindications or underlying medical conditions that may preclude the use of ketamine.

Supervised Clinical Infusion Experience

Although evidence-based didactics are essential for providing safe and effective treatments with ketamine infusion therapy, the best way to gain experience is through supervised clinical practice. To properly understand the complexities behind providing ketamine infusions, our program provides trainees with supervised clinical infusion experience in our infusion center.

Furthermore, the training program provides practical training sessions on properly administering ketamine infusions, including IV insertion techniques and vascular access devices. It also covers the monitoring of patients during and after treatment, including using various monitoring devices such as NIBP, EKG, SpO2, EtCO2, and Capnography.

This "hands-on" training component also complies with APA recommendations. It allows clinicians to have a better understanding of the ketamine infusion process from the perspective of the American Society of Anesthesiologists concerning the administration of sedation by non-anesthesiologists. Additionally, supervised clinical infusion experience allows clinicians to build confidence in their skills, practice communication with patients, and secure a better understanding of the risks associated with ketamine therapy.

An Example of ASA Compliance:

Anesthesiologists Keyword – Vigilance
Patient selection and evaluation for ketamine treatment from an Anesthesiology Perspective
Use of ketamine in special populations
Proper documentation, communication, and collaboration with other healthcare providers
Patient monitoring and safety measures during and after treatment
The critical difference between continual vs. continuous monitoring
IV insertion techniques and the use of vascular access devices
Monitoring – How to use, apply and understand – NIBP, EKG, SpO2, EtCO2, and Capnography
Airway Management from A to Z
Potential adverse effects and side effects of ketamine treatment - What to do in an Emergency

Long-term Effects of Ketamine Use

To further enhance the educational course curriculum on ketamine treatment for mood disorders, the course reviews the limited current research on the long-term effects of ketamine use. Clinicians should be aware of the potential risks and benefits of ketamine treatment in the long run, including its impact on brain function and overall mental health. The American Psychiatric Association encourages clinicians to weigh the risks and benefits of ketamine treatment for mood disorders in light of current scientific literature. Clinicians must remain vigilant in assessing patients to ensure that they are appropriate candidates for ketamine therapy and continue to monitor their progress throughout treatment.

Alternative Treatment Options

Furthermore, the curriculum includes an overview of alternative treatment options for MDD, including traditional antidepressants and psychotherapy, as well as emerging therapies, such as transcranial magnetic stimulation (TMS) and electroconvulsive therapy (ECT). Clinicians should be familiar with the various treatment options and their respective risks and benefits.

Conclusion

The educational curriculum covers important topics related to pharmacology and pharmacokinetics, including the mechanisms of action of ketamine, its pharmacodynamic properties, drug-drug interactions, pharmacokinetic properties, factors that influence ketamine's efficacy, and potential for abuse. It also emphasizes the importance of careful patient selection and evaluation, appropriate documentation of ketamine treatment, communication and collaboration with other healthcare providers involved in a patient's care, adherence to state and federal laws and regulations, and review of the current research on the long-term effects of ketamine.

The program emphasizes the importance of a multidisciplinary approach to ketamine treatment, including collaboration with other healthcare providers such as psychiatrists, psychologists, and primary care physicians. It also provides continuing education and professional development opportunities to ensure clinicians stay up-to-date on the latest research and best practices related to ketamine treatment for mood disorders.

Upon completing the course, clinicians will have the necessary knowledge and skills to provide safe and effective ketamine treatment to patients with MDD who have not responded to other therapies. This includes a comprehensive understanding of the ethical considerations of ketamine for mood disorders and the importance of ongoing evaluation and monitoring of treatment efficacy and potential adverse effects.

Ultimately, this course provides the essentials necessary for safe and effective ketamine treatment for patients with MDD who have not responded to other therapies. Upon successfully completing the course, participants will be able to incorporate the ketamine treatment into their practice and provide safe, effective, and ethical care for patients with MDD who have not responded to other treatments.


To Learn More About Our Programs - please click the links below:

The "Mini-Fellowship" Intensive Training Program

A Detailed Course Overview

Day 1: Ketamine-Based Therapy: The Current State of Ketamine Therapy

Day 2: Ketamine-Based Therapy: Efficacy versus Effectiveness

Day 3: Ketamine-Based Therapy: The Precision Medicine Approach

Our 2023 Course Schedule and How To Apply For Training

New Courses Beginning in 2023

Ketamine Training for Experienced Providers and Anesthesiologists

Improving Ketamine-Assisted Psychotherapy with Precision Medicine

and Target-Controlled Administration Techniques

The Origin of Our Ketamine Training Program

What Our Graduates Say About The Course


"Mini-Fellowship" Intensive Ketamine Infusion Training for Clinicians

3-Day Intensive Course

Our course not only covers all of the practical aspects of ketamine therapy but expands into scientific principles allowing optimization of the basic protocol.  All course training is conducted “on-site” in an actual infusion center so that you will have an opportunity to become familiar with the environment in which infusions are performed and obtain valuable clinical experience administering ketamine infusions under expert supervision. This includes utilizing all of the necessary monitoring equipment, intravenous delivery systems, and supplies necessary for the safe administration, storage, and handling of ketamine. 

How to effectively integrate ketamine therapy into your current practice

Download Course Brochure

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The Ketamine Institute

The Ketamine Institute is leading the way in the field of ketamine infusion therapy and physician education with our new ketamine infusion training program. We’re on a mission to accelerate the health care revolution. We have pioneered ketamine infusion therapy to bring the latest breakthrough discoveries about ketamine out of the research lab and into our infusion centers.


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