The Ketamine Infusion

Learn About the Ketamine Infusion


ketamine picture


The ketamine infusion for mood disorders most commonly used today was initially developed at the Yale University School of Medicine in 1994.  In 1999-2000 it was discovered to be rapidly effective for treating mood disorders such as depression, anxiety, and PTSD.  It has since become known as the "standard" ketamine infusion and is used by the National Institute of Mental Health, major universities, and ketamine centers worldwide.

standard ketamine infusion series

Currently Used To Treat:

Depression      Bipolar Illness      Anxiety      PTSD

Standard Ketamine Infusion – Basic. 6 Infusions/14 Days Series Includes -

The Standard Ketamine Infusion includes all aspects of care as recommended by the American Psychiatric Association and the American Society of Anesthesiologists, this includes:

Initial Evaluation:
Detailed Initial screening and assessment.
Review of medical records, depression, anxiety, and pain metrics.
Review of preliminary laboratory tests and evaluations.

Standard Ketamine Infusion:
Standard ketamine infusion – Yale-National Institute of Mental Health Protocol
Infusion with consideration of your current medications and body weight.

Physician supervised -
RN/Staff present with continual visual and vital signs monitoring, including:
Heart rate
Blood pressure
Pulse Oximetry

Meets all recommendations:
American Psychiatric Association-
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders
American Society of Anesthesiologists-
Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists

Staff - Post infusion assessment

Post-Infusion Maintenance Therapy:
A patient generally does best with regular maintenance infusions scheduled monthly.

Maintenance Therapy:

Requires continued regular maintenance infusions - usually every month.
Patients generally do best with regular maintenance infusions scheduled monthly. Regularly scheduled maintenance infusions help to maintain the benefits achieved during the initial therapy.  Of course, if something happens, such as a very stressful life circumstance or traumatic event, then additional infusions may be needed more frequently for a short time.


Simple – Standard amount of medication based on body weight - may vary slightly on occasion.
Effective – 70% of our patients experience improvement in their symptoms- only 50-60% may improve at other centers due to variations in treatment protocols and procedures.
Reduced Medication – Some patients may find they can reduce or discontinue prior medications that were not helpful.
More Common – Because the standard ketamine infusion is becoming more widely recognized as an effective treatment and more physicians are offering it, so it may be available near you.


The initial time commitment (two weeks) can be a barrier. Also, the benefits are often only temporary, so you may require ongoing treatment each month which can become expensive for many people. There is also the possibility that with repeated monthly exposure to ketamine, over time you may develop increasing tolerance or resistance to the drug and lose the benefits.

Note - The standard ketamine infusion is not significantly or consistently effective for the treatment of migraines, painful neuropathy, fibromyalgia, RSD/CRPS, or other types of neuropathic pain syndromes.


Total cost for initial assessment and 6 infusions -14-day treatment series – $2650.00 USD
Maintenance infusions are $400.00

*Now that you know the advantages of RESTORE, if you still feel that regular ketamine
infusion therapy is an option for you, then please
read our guide on
How to Choose The Best Ketamine Infusion Center - 2021.

Now that you know a little more about the Ketamine Infusion, explore our other options

Standard Ketamine Infusion


“The most important breakthrough in antidepressant treatment in decades”....

Thomas Insel, MD - Director, National Institute of Mental Health

Tag Line RRR