Ketamine Research Institute Training Program

Welcome to the final day of training!

The Precision Medicine Approach

Day 3 Overview: Mastering Ketamine Therapy Through Personalization and Precision

Modules 5 and 6: The Keys to Transformative Ketamine Practice

Day 3 of our ketamine training course focuses on the critical variables that determine ketamine efficacy and the power of personalized medicine. This day is designed to equip clinicians with advanced knowledge and practical tools to optimize ketamine therapy for each patient, making it an essential component of the training program.


Module 5 - Transform Your Approach: The Critical Variables That Drive Ketamine Efficacy

This module delves into the key factors influencing ketamine's effectiveness, including body mass, drug interactions, comorbidities, metabolism, genetics, and patient mindset. Clinicians will learn to fine-tune their approach to each patient, ensuring the therapy is tailored to their needs.

This module also covers advanced criteria for patient selection, the role of diagnostics and genetics, and the importance of biomarkers in guiding precision treatment. Additionally, we address the risks of tolerance, tachyphylaxis, and the hormesis effect, providing strategies to manage and prevent these challenges. By mastering these variables, clinicians can significantly enhance the outcomes of their ketamine therapy.


Inside Module 5:

Uncovering the Critical Variables: How to Fine-Tune Ketamine Therapy for Best Results
• Mass
- Mass Matters: The Impact of Body Weight on Ketamine Dosing
• Medications
- Drug Interactions 101: How Medications Influence Ketamine's Efficacy
• Morbidity
- Managing Comorbidities: Essential Considerations for Ketamine Therapy
• Metabolism and Genetics
- The Genetic Blueprint: How Metabolism Affects Ketamine Outcomes
• Mindset
- Mind Over Medicine: The Role of Psychological Factors in Ketamine Therapy

The Solution: Optimizing Patients and Targeting Your Infusion
• Personalized Medicine: A New Frontier in Ketamine Therapy
• Enhanced Patient Selection/Evaluation Criteria
• Selecting the Right Patients: Advanced Criteria for Ketamine Therapy
• Setting the Stage: The Role of Diagnostics and Genetics in Ketamine Therapy
• Biomarkers in Focus: Guiding Precision in Ketamine Therapy

Navigating the Risks: Essential Cautions in Ketamine Therapy
• Tolerance
- Understanding Tolerance: Managing Long-Term Ketamine Use
• Tachyphylaxis
- Combatting Tachyphylaxis: Preventing Rapid Diminished Response in Ketamine Therapy
• Hormesis
- Mastering the Dose-Response Curve: The Inverted "U" Phenomenon in Ketamine Therapy


Module 6 - Revolutionizing Ketamine Therapy: The Power of Personalized Medicine and Targeted Infusions

The final module focuses on the application of precision dosing and targeted infusions across various disorders, including anxiety, PTSD, depression, bipolar disorder, fibromyalgia, and chronic pain conditions.

Clinicians will learn how to create the ideal ketamine experience for their patients, using frameworks of reference, multi-sensory stimulation, and precision monitoring to optimize the therapy. This module also includes a recap of ketamine infusion techniques, emphasizing why the personalized approach surpasses standard protocols.

To ensure clinicians are fully prepared, we provide a rapid guide to successful first infusions, advanced treatment protocols, and a quick reference guide for effective ketamine therapy. The day concludes with a focus on the importance of mentoring and marketing to grow a successful ketamine practice.


Inside Module 6:

Precision Dosing: Achieving Optimal Plasma Concentrations for Each Disorder
• Ketamine-Assisted Psychotherapy: The Role of TDI in Ketamine-Assisted Psychotherapy
• Anxiety – PTSD: Targeted Ketamine Strategies for Rapid Relief
• Depression – Bipolar Disorder: Rapid Breakthrough with Targeted Ketamine Therapy
• Fibromyalgia: Relieving Fibromyalgia Pain
• Chronic Pain Conditions: Proceed with Caution

Elevating Patient Experience: Techniques to Enhance the Ketamine Journey
• Creating the Ideal Ketamine Experience: Frameworks of Reference and Techniques for Success
• The Framework of Reference
• Guiding the Ketamine Experience: How to Assist When Needed
• Precision Monitoring: Techniques to Optimize Ketamine Infusions
• Enhancing Ketamine's Impact: The Power of Multi-Sensory Stimulation
• Mapping the Journey: Understanding the Typical Course of a Ketamine Infusion

Ketamine Infusion Therapy – Recap
Revisiting Ketamine Infusions: Why the New Approach Outshines the Standard

Putting It All Together: A Rapid Guide to Your First Infusion
• Optimize from the Start: Ensuring Success at the First Ketamine Encounter
• Advanced Treatment Protocols: A Step-by-Step Ketamine Algorithm
• The Clinician's Quick Reference Guide to Effective Ketamine Therapy

Mentoring Program and Marketing
Grow Your Practice: The Power of Mentoring and Marketing in Ketamine Therapy


Why Choose This Course: Becoming A Ketamine Expert

Day 3 is critical for clinicians who want to master the art and science of ketamine therapy. By focusing on the key variables that drive efficacy and the application of personalized medicine, this training ensures that participants can offer their patients the most effective and tailored treatment. The combination of cutting-edge knowledge, practical application, and comprehensive support makes this course unmatched in its ability to prepare clinicians for successful ketamine therapy practice.


Clinical and Experiential Session – Day 3

Day 3 Overview: From Theory to Practice – Elevate Your Clinical Skills with Hands-On Experience

Clinical and Experiential Sessions: Gain Unmatched Expertise in Ketamine Therapy
Days 2 and 3 of our ketamine training course are dedicated to transforming theoretical knowledge into practical expertise. These sessions offer clinicians an unparalleled opportunity to engage in supervised clinical training and experience ketamine's effects firsthand. This combination of hands-on practice and personal immersion ensures that participants develop the competence and confidence needed to excel in ketamine therapy.

Supervised Clinical Training: Mastering the Art of Ketamine Infusions

In addition to our advanced didactic sessions, clinicians will receive advanced training under expert supervision, mastering every aspect of the ketamine infusion process—from meticulous pre-procedure preparation to precise infusion techniques and thorough post-procedure care.

You'll learn to create the optimal infusion environment, fine-tune dosing, and manage psychological and physiological responses during treatment. This real-world application of advanced pharmacokinetic modeling and electronic infusion records sets this course apart, providing you with the skills to deliver safe, effective, and patient-focused care.

Elevate Your Skills with Actual Ketamine Infusion Practice

This advanced ketamine infusion training module offers clinicians unmatched hands-on experience and comprehensive knowledge, surpassing what other programs provide. Under expert supervision, you'll master every aspect of the infusion process—from meticulous pre-procedure preparation to precise infusion techniques and thorough post-procedure care.

Master Ketamine Infusions: Hands-On Training with Expert Supervision

Learn to create the optimal infusion environment, fine-tune rates and concentrations, and manage psychological and physiological responses during treatment. The module also covers advanced pharmacokinetic modeling and state-of-the-art electronic infusion records, ensuring you deliver safe, effective, and patient-focused care. With a strong emphasis on real-world application, this training equips you with the skills and confidence to excel in ketamine therapy, providing a level of instruction that sets you apart in the field.


Inside the Clinical Session – Day 3

Perfecting the Setup: A Guide to Pre-Infusion Preparation
• Preparation of the infusion suite
• The Pre-Procedure Checklist for Ketamine Infusions
• Step-by-Step Suite Setup and Setting up Your Infusion Tray
• Enhance the Experience: Using AV Tools to Optimize Ketamine Therapy
• Pre-procedure patient preparation
• The Crucial First Step in Ketamine Therapy: Determination of Adjusted Body Weight
• Precision Dosing: Accurately Determining Target Plasma Concentrations
• Positioning Perfection: How to Ensure Patient Comfort and Safety
• Mastering Vital Signs Monitoring: Application and Adjustment Techniques
• Pre-Treatment Vitals: Your Final Check Before Infusion

The Art of Infusion: Essential Techniques for Ketamine Therapy
• A Complete Guide for Clinicians: From IV Access to Patient Monitoring
• Precision Access: Mastering IV Insertion Techniques for Ketamine Infusions
- Infusion methodologies: Gravity, Drip Assist, Infusion pumps
• Targeting Precision: How to Determine Ideal Ketamine Plasma Levels
- Pharmacokinetic modeling during infusion
• Infusion Intelligence: Using Pharmacokinetics for Optimal Dosing
- Using the electronic ketamine infusion record
• Real-Time Assessment: Monitoring Psychological and Physiological Responses
- Assessment of your patient's level of consciousness
• Stay Alert: Techniques for Assessing Consciousness During Ketamine Infusions
- How to perform infusion rate or concentration adjustments
• Precision Adjustments: Fine-Tuning Infusion Rates and Concentrations
- Preventing infusion occlusions, flow reductions, and disconnects
• Smooth Sailing: Preventing and Managing Infusion Complications
- Tips for guiding patients through the infusion
• Guiding Patients: Best Practices for a Positive Infusion Experience
- Avoiding and managing adverse effects
• Proactive Prevention: Strategies for Managing Adverse Effects

After the Infusion: Key Steps for a Smooth Recovery
• Managing Recovery: Best Practices for Post-Infusion Care
• The Critical Post-Infusion Phase: Ensuring Patient Comfort and Safety
• Navigating Recovery: Addressing Nausea, Fatigue, and Disequilibrium
• Beyond the Infusion: Effective Debriefing and Integration Techniques
• Keeping a Close Watch: Best Practices for Post-Infusion Monitoring
• Safe and Sound: Best Practices for Patient Transport and Discharge


Experiential Session – Day 3

Stepping into Your Patients' Shoes

What truly differentiates this course from all others is the opportunity for clinicians to experience ketamine's profound effects themselves. By personally navigating the non-ordinary states of consciousness induced by ketamine, you'll gain invaluable insights into the patient experience.

This firsthand understanding enables you to prepare better and support your patients, reducing their anxiety and increasing the efficacy of the treatment. No other training program offers this level of immersive learning, making it a critical component for clinicians who aim to provide the highest standard of care.

Experience Ketamine Firsthand and Transform Your Practice

By combining this direct experience with the extensive didactic knowledge and hands-on supervised clinical training provided in the course, clinicians gain invaluable insights that are critical for developing the competence and expertise necessary to accurately assess the appropriateness and tailor the application of ketamine therapy for their patients. This unique, immersive approach sets this program apart, providing an essential foundation no ketamine infusion training offers.


The Key Benefits You'll Gain Can Be Invaluable:

Framing the Ketamine Experience
• Framing the Ketamine Experience sets the stage for a therapeutic journey with clear intentions and expectations, whether it's for treating depression, managing pain, or exploring psychological states. Clinicians who have personally experienced ketamine's effects are better equipped to guide their patients, helping them mentally and emotionally prepare. This firsthand understanding allows clinicians to reduce patient anxiety and increase the receptivity and effectiveness of the treatment.

Valuable Tips for Beginning an Infusion Session
• Starting an infusion session correctly is crucial for safety and maximizing outcomes. Clinicians who have undergone the infusion themselves understand the importance of creating a calm, supportive environment. Their experience enables them to establish rapport quickly and effectively, accurately set up the infusion, and address any patient concerns, ensuring the session begins on the right foot.

Visual, Kinesthetic, and Somatic Processing
• Ketamine often heightens sensory perceptions, such as visual imagery, bodily awareness, and emotional responses. Clinicians who have experienced these effects can better support their patients by tailoring the therapeutic environment and providing guidance through intense sensations. This insight helps them create a more personalized and effective treatment experience.

Experiencing Dissociation
• Dissociation, where patients may feel detached from their body or reality, is a key effect of ketamine. Clinicians who have experienced this can better prepare patients, explaining what to expect and how to navigate it. This personal understanding allows clinicians to ensure dissociation becomes a safe, therapeutic part of the process rather than a source of anxiety.

Time and Space Expansion
• Ketamine can alter perceptions of time and space, making them feel fluid and expansive. Clinicians who have felt these shifts can help patients understand and embrace these changes, turning what might be disorienting into a therapeutic tool for gaining new perspectives.

Non-linear Thought
• Ketamine can disrupt linear thinking, leading to what appears to be fragmented, non-sequential thoughts. Clinicians who have experienced this can guide patients through these cognitive shifts, helping them find meaning in the ketamine space and uncover new insights rather than feeling overwhelmed by the change in thought patterns.

The Ketamine Continuum and Depth of Immersion
• Patients can experience varying depths of immersion during an infusion, from mild perceptual changes to deep states of consciousness. Clinicians who have explored these depths can better assess and modulate the experience for their patients, ensuring the therapy is tailored to their specific needs and therapeutic goals.

The Spacious Present
• The "spacious present" is where patients feel fully immersed in the moment, free from past and future concerns. Clinicians who have entered this state themselves can guide patients to embrace this therapeutic space, where significant emotional and psychological healing can occur.

Debriefing and Integration Techniques
• Debriefing and integration are critical for processing the experiences and insights gained during an infusion. Clinicians who have undergone this process can better help patients articulate their experiences and integrate them into their lives, enhancing the lasting impact of the therapy.

Returning from the Experience
• Guiding patients back to ordinary consciousness after an infusion is a delicate process. Clinicians who have experienced this transition understand the importance of a gentle, supportive approach, helping patients feel grounded and ready to integrate the experience.

Post-infusion Phenomena
• Post-infusion effects like mild dissociation or new insights are common. Clinicians who have experienced these phenomena can provide better care by reassuring patients and helping them navigate these residual effects, maximizing the therapeutic benefits.

Learning from Insights Gained to Adjust Subsequent Infusion Sessions
• Each ketamine session offers insights that can improve future treatments. Clinicians who have experienced ketamine themselves can better help patients reflect on their experiences, adjusting future sessions to meet evolving needs for more effective, personalized outcomes.


Why This Course Exceeds Expectations

This training program is unparalleled in its comprehensive approach, combining rigorous clinical practice with deep personal experience. By the end of Days 2 and 3, you'll have the technical skills and the empathetic understanding needed to excel in ketamine therapy. This unique blend of knowledge and experience

Click here to go to the course schedule and application page


Here's What Our Graduates Have To Say

"Dr. Grass:

This is just a token of appreciation for your time and patience. When I enrolled in your program, it was not my intent to participate by exhaustively asking questions, but it became apparent that I had overestimated my fund of knowledge.

Although I have extensive clinical experience with ketamine, and I work at expanding my understanding of the fundamental physiology and pharmacology involved in the administration of ketamine for mental health disorders, I had no idea how much I didn't know.

All the knowledge that I had acquired needed the perspective and clinical understanding that you were willing to share. Thanks again for your help.

Your program exceeded all expectations"

— Mark Garwin, MD - Anesthesiologist


To Learn More About Our Programs - please click the links below:

The "Mini-Fellowship" Intensive Training Program

A Detailed Course Overview

Day 1: Essential Foundations for Ketamine Therapy

Day 2: Mastering the Future of Ketamine Therapy

Day 3: Personalization and Precision in Ketamine Therapy

Our Course Schedule and How To Apply For Training

The Origin of Our Ketamine Training Program

What Our Graduates Say About The Course

How the Ketamine Research Institute Training Program Complies with APA and ASA Recommendations


"Mini-Fellowship" Intensive Ketamine Infusion Training for Clinicians

3-Day Intensive Course

Our course not only covers all of the practical aspects of ketamine therapy but expands into scientific principles allowing optimization of the basic protocol.  All course training is conducted “on-site” in an actual infusion center so that you will have an opportunity to become familiar with the environment in which infusions are performed and obtain valuable clinical experience administering ketamine infusions under expert supervision. This includes utilizing all of the necessary monitoring equipment, intravenous delivery systems, and supplies necessary for the safe administration, storage, and handling of ketamine. 

How to effectively integrate ketamine therapy into your current practice

Download Course Brochure

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The Ketamine Institute

The Ketamine Institute is leading the way in the field of ketamine infusion therapy and physician education with our new ketamine infusion training program. We’re on a mission to accelerate the health care revolution. We have pioneered ketamine infusion therapy to bring the latest breakthrough discoveries about ketamine out of the research lab and into our infusion centers.


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A New Therapeutic Option for Depression and Pain

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