The RESTORE Essential Infusion

Learn About the RESTORE Essential Infusion


The RESTORE Essential Infusion is a more sophisticated and innovative formulation of the ketamine infusion program, incorporating innovative genetic, metabolic and medication assessments and optimized infusion protocols to increase efficacy in complex and challenging conditions that have been resistant to other conventional treatment approaches.

Not everyone reacts to medications in the same way. Many people experience feelings of frustration when they don’t receive relief after trying multiple antidepressants, or other treatment such as TMS, ECT, Spravato or standard ketamine infusions.

The RESTORE Essential Program provides many of our patients with relief of their symptoms for 1-3 years or more - unlike ketamine infusions which typically only last 4-6 weeks.  It is highly recommended for patients with severe depression, anxiety, panic disorder or complex PTSD who have not respond to:-

8 or more antidepressant medications
Transcranial Magnetic Stimulation (rTMS)
Electroshock Therapy (ECT)
Standard ketamine infusions

And those who are currently prescribed:

Stimulants: Vyvanse, Adderall, Ritalin, Dexedrine, Concerta, Strattera or
Mood Stabilizers: Lamictal, Risperdal, or Zyprexa

In these challenging conditions successful infusion therapy must be custom tailored to the individual and the specific medical condition to achieve the best effect. The RESTORE Essential Infusion program provides a detailed, personal evaluation that may include obtaining a sophisticated genetic and metabolic profile with specific recommendations and assistance with optimization prior to beginning infusion therapy to achieve long lasting relief.

In addition to metabolic and genetic optimization of each patient we see, each RESTORE Essential infusion is administered directly by our physicians using a proprietary 3-stage infusion protocol with continual adjustment, providing the optimal concentration of medication necessary for complex conditions over a longer period of time.

That is why RESTORE Essential can achieve rapid symptom relief for those who have not improved with multiple antidepressants, rTMS/ECT treatments or prior ketamine infusions.

RESTORE Essential can accomplish in just 3 sessions what others may not be able to achieve with 6-9 or more ketamine infusions.  Not only that, the benefits of feeling better last much longer than those seen with the basic ketamine infusion.

Currently Used To Treat:

Mood Disorders:                         Has Been Helpful in:                         
Depression                                    Fibromyalgia
Bipolar Illness                               Migraine Headaches

RESTORE Essential Infusion Series Includes -

Initial Evaluation:
Comprehensive Initial screening and assessment:
Review of medical records, depression, anxiety and pain metrics.
Review of all prior laboratory tests and evaluations.

Also includes -
Review and optimization of critical metabolic issues including thyroid hormone levels, testosterone/estrogen levels, Vitamin D, B6 and B12 levels as necessary. Additional testing for acetyl-L-carnitine or ALCAR and Magnesium levels.
In challenging presentations, it may also require Genomind genetic profile analysis for Cytochrome P450 function; serotonin, dopamine and norepinephrine receptor variants and, MTHFR/BDNF variant screen.
Comprehensive treatment plan including extensive consultation with each patient and family members regarding infusion protocol and infusion experience.

Infusion Series:
RESTORE Essential three-part sequential optimized infusion

Each infusion is optimized to each patient's individual physiological and psychological response based upon pharmacokinetic parameters.

Also includes - 
Pre-Infusion analysis:
Genomic Profile: Infusion optimization per current medications, sex, and adjusted body composition and prior treatment history.
Pharmacokinetic Optimization: Each infusion is optimized based on computer modeling of blood level concentrations.
Pharmacodynamic Monitoring: Each infusion is monitored and adjusted based upon psychological and physiological response.

Physician is always present with each patient:
Continual real-time monitoring, including
Heart rate and heart rate variability
Blood pressure
Pulse Oximetry

Also includes -
Autonomic nervous system monitoring and assessment
Pharmacokinetic monitoring
Reassessment of pharmacokinetic profile and response
Ongoing infusion adjustments and modifications.
Acoustic and visual modification and entrainment
RESTORE proprietary booster supplement.

Meets and exceeds recommendations:
American Psychiatric Association-
A Consensus Statement on the use of Ketamine in the Treatment of Mood Disorders
American Society of Anesthesiologists-
Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists

Post infusion assessment by attending physician

Also includes - 
Review of physiological and psychological response
Review of pharmacokinetic and Pharmacodynamic response
Inter-Infusion re-evaluations and reassessments by physician.

Maintenance Therapy:

The fewer maintenance infusions are needed –
After the first 3 infusions, patients' generally require only 2 infusions at the 3 month mark and 1 infusion at the 6 month mark to become very long lasting (1-3 years in many cases). Of course, if something happens such as a very stressful life circumstance or traumatic event, then subsequent infusion may be needed for a short time.


Long Term Relief - Following the 3 initial infusions, there are only two maintenance sessions needed to obtain longer term relief.  Session 1 - Two infusions are performed at the three month mark following the initial series and then Session 2 - One infusion is performed at the 6 month mark.  This advanced program provides many of our patients with relief lasting 1-3 years or more.

Very Effective – 85% of patients’ with complex or challenging conditions can experience improvement in their symptoms - even in those who have not responded to prior ketamine treatments, ECT or transcranial magnetic stimulation (rTMS).
Very Rapid – Only requires 3 infusions, given over 3 days to complete
Very Long Lasting – Improvements last much longer than any ketamine infusion, very few maintenance infusions are needed.
Cost Effective – Initial Series and maintenance infusions cost much less over the first year of treatment than multiple ketamine infusions.
Time Effective –Less time away from home and work
Reduced Medication – Most patients find they can reduce or discontinue prior medications that were not helpful.


At the present time it is only available at the Ketamine Institute in Sarasota, FL, but we do plan to make it available at multiple locations in the future.


The total cost of the RESTORE Essential Infusion treatment is $3450.00 USD
Once the initial therapy is completed and each person’s optimal response level is determined, the cost of the maintenance infusions is $725.00.


Now that you know a little more about the RESTORE Essential Infusion, explore our other options

Standard Ketamine Infusion

That is the RESTORE Essential Infusion difference.

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