Learn About the RESTORE Advanced Infusion


The RESTORE Advanced Infusion is the most effective, efficient, and rapid infusion therapy available.  It was developed over 20 years of clinical research to effectively treat a wide variety of pain-related issues in the most efficient manner possible.

We discovered in 2002, that successful infusion therapy must be custom-tailored to the individual and the specific medical condition to achieve the best effect.  To do that, we spent years of clinical research determining the most effective dose and method for each specific condition.  But more than that, we also knew that each person responds to medication differently.  Because of that, we carefully consider current medications, each person’s basic metabolism, and genetic profile to optimize each infusion for that individual patient.

In addition to metabolic and genetic optimization of each patient we see, the RESTORE infusion process is a unique combination of concentrated ketamine and magnesium additives to make it more effective, that it is then administered by our physicians using a proprietary infusion protocol to provide the optimal blood levels for a longer period of time. That is why RESTORE is faster acting, more effective, and longer-lasting than any regular ketamine infusion. And the beneficial results can begin in just minutes to hours after the first infusion.

More than that, we also employ a specialized environment to enhance the effectiveness of our infusions that include proprietary synergist medications and protocols during each infusion session for maximal effectiveness.  These factors allow us to accomplish in just 3 sessions what others may not be able to achieve with 6 or more infusions.  Not only that, the benefits of feeling better last much, much longer than those seen with the ketamine infusion.

Currently Used To Treat:

Chronic Pain:                         Has Been Helpful in:
Fibromyalgia                          IBS - Irritable Bowel Syndrome
Migraine Headaches            CFIDS/ME - Chronic Fatigue Syndrome, Long COVID
Neuropathy                            Inflammatory Arthritis
RSD/CRPS                             Pelvic Pain - Vulvodynia - Pudendal Neuralgia

Special Categories

Prior Ketamine Infusion Treatment Failures

Complex OCD/Anxiety/PTSD Presentations

RESTORE Advanced  3-day Intensive Infusion Series Includes -

Initial Evaluation:
Comprehensive Initial screening and assessment:
Review of medical records, depression, anxiety, and pain metrics.
Review of all prior laboratory tests and evaluations.

Also includes -
Review and optimization of critical metabolic issues including thyroid hormone levels, testosterone/estrogen levels, Vitamin D, B6 and B12 levels as necessary. Additional testing for acetyl-L-carnitine or ALCAR, hsCRP may also be recommended.
May also include Genecept Cytochrome P450 analysis and BDNF/MTHFR variant screen.
Comprehensive treatment plan including extensive consultation with each patient and family members regarding infusion protocol and infusion experience.

Infusion Series:
RESTORE Advanced Ultra-Rapid three-part sequential enhanced and optimized infusion

Each infusion is optimized to each patient's individual physiological and psychological response based upon pharmacokinetic parameters.

Also includes - 
Pre-Infusion analysis:
Genomic Profile: Infusion optimization per genetic profile, current medications, sex, and adjusted body composition and prior treatment history.
Pharmacokinetic Optimization: Each infusion is optimized based on computer modeling of blood level concentrations.
Pharmacodynamic Monitoring: Each infusion is continually monitored and adjusted based upon psychological and physiological response.
Synergistic Agents: Synergistic medications used as indicated to increase the effectiveness and durability of basic ketamine.

Physician always present with each patient:
Continual real-time monitoring, including
Heart rate and heart rate variability
Blood pressure
Pulse Oximetry

Also includes -
Proprietary Optimization Protocol:
Restore Adjuvant administration
Autonomic nervous system monitoring and assessment
Pharmacokinetic monitoring
Reassessment of pharmacokinetic profile and response
Continual, minute-to-minute infusion adjustments and modifications.
Intra-infusion cognitive reframing and enhancement.
Acoustic and visual modification and entrainment.
May also include EEG alpha/theta suppression surveillance rates/data adjustment.

Meets and exceeds recommendations:
American Psychiatric Association-
A Consensus Statement on the use of Ketamine in the Treatment of Mood Disorders
American Society of Anesthesiologists-
Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists

Post infusion assessment by attending physician

Also includes - 
Review of physiological and psychological response
Review of pharmacokinetic and Pharmacodynamic response
Spatial and Chromatic analysis of subjective infusion experience
Inter-Infusion re-evaluations and reassessments by physician.

Post Infusion Maintenance:
RESTORE supplement oral suspension – enhances effectiveness and prolongs duration of improvements

Maintenance Therapy:

The fewest maintenance infusions are needed –
After the first 3 infusions, patients generally require only 2-3 maintenance infusions. After that, the beneficial changes become even longer lasting and fewer if any infusions are needed. Of course, if something happens such as a very stressful life circumstance or traumatic event, then subsequent infusion may be needed for a short time.


Very Effective – 75%+ of patients’ experience improvement in their symptoms
Very Rapid – Only requires 3 infusions, given over 3 days to complete
Longer Lasting – Improvements last for months to years, no need for frequent maintenance infusions
More ComprehensiveRESTORE Advanced Infusion is effective for many more conditions than the standard infusion or the RESTORE Essential Infusion
Cost Effective – Initial Series and maintenance infusions cost less over the first year of treatment than any other option.
Time Effective –Less time away from home and work
Reduced Medication – Most patients find they can reduce or discontinue prior medications that were not helpful.


Only available at the RESTORE Infusion Center - Ketamine Research Institute in Sarasota, FL at the present time.


The total cost of the RESTORE Advanced Infusion program is $4450.00 USD
Once the initial therapy is completed and each person’s optimal response level is determined, the cost of the maintenance infusions is only $750.00.

*Now that you know the advantages of RESTORE, if you still feel that regular ketamine
infusion therapy is an option for you, then please
read our guide on
How to Choose The Best Ketamine Infusion Center - 2021.


Now that you know a little more about the RESTORE Advanced Infusion, explore our other options

That is the RESTORE Advanced Infusion difference.

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