Current Scientific Research Articles
The published research behind
RESTORE Infusion Therapy
We cannot solve our problems with the same thinking we had when we created them
- - Albert Eistein
Long-term outcome in outpatients with depression
treated with acute and maintenance intravenous ketamine:
A retrospective chart review. - Only 18.3% Effectiveness
Sakurai H, et al. J Affect Disord. 2020 Nov 1;276:660-666.
doi: 10.1016/j.jad.2020.07.089. Epub 2020 Jul 20.
PMID: 32871698.
Acute and Longer-Term Outcomes Using Ketamine
as a Clinical Treatment at the Yale Psychiatric Hospital
- Only 45.5% Effectiveness
Wilkinson ST, et al. J Clin Psychiatry. 2018 Jul 24;79(4):17m11731.
doi: 10.4088/JCP.17m11731. PMID: 30063304
A Dynamic Network Perspective of Chronic Pain
Farmer MA, Baliki MN, Apkarian AV.
Neuroscience Letters June 2012;520(2): 197-203
Functional Reorganization of the Default Mode Network across Chronic Pain Conditions
Baliki MN, Mansour AR, Baria AT, Apkarian AV.
PLOS One, September 2014; Volume 9; Issue 9
Shape shifting pain: chronification of back pain shifts brain representation from nociceptive to emotional circuits
Hashmi JA, Baliki MN, Apkarian AV. et al
Brain 2013: 136; 2751-2768
Functional and structural imaging of pain-induced neuroplasticity
Seifert F, Malhotner.
Current Opinions in Anesthesiology 2011; 24: 515-528
Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants
Browne CA, Lucki I.
Frontiers in Pharmacology December 2013; Vol 4:161
Subanesthetic Ketamine Infusion Therapy: A Retrospective Analysis of a Novel Therapeutic Approach to Complex Regional Pain Syndrome
Correll GE, Maleki J, Harbut RE, et al.
Pain Medicine 2004; Volume 5 (3): 263-275
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder; A Randomized Clinical Trial
Adriana F, Parides MK, Murrough JW, et al.
JAMA Psychiatry 2014;71(6):681-688
Ketamine psychotherapy for heroin addiction: immediate effects and two-year follow-up
Krupitsky EK, Burakov A, Romanova T, et al.
Journal of Substance Abuse Treatment 2002; Volume 23:273-283
Effects of ketamine on explicit and implicit cognition: A randomized controlled trial in treatment resistant depression
Price RB, Iosifescu DV, Murrough JW., et al
Depression Anxiety 2014;31(4):335-343
Ketamine as a promising prototype for a new generation of rapid-acting antidepressants
Abdallh CG, Averill LA, Kyrstal JH.
Annals Of The New York Academy of Sciences 2015; Issue - Translational Neuroscience in Psychiatry:1-12
Ketamine Safety and Tolerability in Clinical Trial for Treatment-Resistant Depression
Wan L, Levitch CF, Perez AM, et al.
Journal of Clinical Psychiatry 2015;76(3):247
Safety and Efficacy or Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression
Rot M, Collins KA, Murrough JW, et al.
Biological Psychiatry 2010; 67: 139-145
The Ketamine Research Institute
On the current of ketamine therapy with RESTORE