The Essential Training Needed to Achieve Superior Results with Ketamine Therapy

The KRI Mini-Fellowship: Beyond Certification—Toward Clinical Mastery

Adding ketamine therapy to your practice isn’t just a procedural shift—it’s a clinical, ethical, and strategic decision that demands more than a weekend course. The KRI Mini-Fellowship is the only ketamine training program in the U.S. that fully meets the American Psychiatric Association and American Society of Anesthesiology standards, and it’s built to do one thing: ensure you're prepared to deliver safe, effective, and outcome-driven ketamine care from day one.

A Program Designed for Clinicians Who Want to Do It Right

Many programs teach the basics. Few prepare you for real-world complexity. Most rely on outdated, standardized dosing protocols that lead to suboptimal outcomes—where fewer than 40% of patients improve, and up to 8% worsen. We teach a different approach: individualized, precision-based care informed by pharmacokinetics, metabolism, comorbidities, and real-time clinical observation.

What You Gain—Clinically and Professionally

➤ Mastery Through Experience and Mentorship
Spend three intensive days at our infusion center learning hands-on from expert faculty. Then, continue refining your practice with 12 months of direct support, including clinical consultations, business guidance, and mentorship. You're not left to figure it out alone.

➤ Clinical Tools That Actually Work
Receive comprehensive, ready-to-use protocols, evaluation templates, safety checklists, SOPs, and a proprietary pharmacokinetic dosing calculator—everything needed to launch or optimize your program without guesswork safely.

➤ Techniques That Set You Apart
Go beyond the outdated 0.5 mg/kg model. Learn target-determined infusions, genetic and lab-guided adjustments, and strategies to mitigate adverse effects—allowing you to consistently deliver better outcomes and gain more referrals.

➤ A Unique Patient-Centered Perspective
Unlike other programs, you’ll also personally experience a ketamine infusion under supervision. This rare opportunity builds empathy, insight, and a deeper understanding of the patient journey—translating into stronger therapeutic alliances.

➤ Recognition That Follows You
Graduates earn KRI certification, a listing in our national clinician directory, and access to a network of peers committed to excellence in ketamine therapy—adding instant credibility to your practice.

It positions you not just to offer ketamine therapy—but to offer it safely, skillfully, and successfully, with the kind of confidence and outcomes that elevate both patient care and your professional standing.

Your Next Patient's Breakthrough Begins With Your Decision Today

Don't let another patient leave feeling hopeless when you can offer a genuine transformation. Join forward-thinking clinicians who are redefining what's possible in mental healthcare. And build the practice you've always envisioned, where your expertise creates life-changing results and hope.

Because your patients deserve transformation, not mere maintenance.

The Premier Ketamine Therapy Training Course for Clinicians

If you’re a Primary Care clinician seeking to revolutionize your practice and establish yourself as an expert in ketamine therapy, look no further. The Ketamine Research Institute’s "Mini-Fellowship" Intensive Training Program is not just another ketamine course—it’s the definitive pathway to clinical excellence, patient satisfaction, and professional recognition in this rapidly evolving field. The Mini-Fellowship Intensive is the most advanced and comprehensive ketamine training available—designed for clinicians serious about mastering precision-based, high-impact therapy.

Unlike online-only courses, this program provides a comprehensive blend of didactic instruction, immersive hands-on clinical experience, and personalized mentoring. Clinicians are trained using a cutting-edge approach to Personalized Medicine and Targeted Infusion Therapy, learning not only the fundamentals but also advanced pharmacokinetic modeling, precision dosing, and patient-tailored protocols. This ensures you can deliver safer, more effective, and better-tolerated treatments, setting your practice apart from typical "one-size-fits-all" protocols.

Our Invaluable Tools for Success in Ketamine Therapy include:

The Complete Clinical Reference Manual of Ketamine: From Theory to Practice

The Ketamine Research Institute training manual represents a comprehensive compendium of advanced ketamine knowledge, authored by Dr. Gerald W. Grass, MD, Medical Director of KRI. The manual serves as an invaluable reference source, consolidating cutting-edge research, pharmacokinetic principles, and a mechanistic understanding of ketamine's complex therapeutic actions across multiple clinical applications.

The manual serves as both an educational resource and a detailed pharmacological reference, covering advanced topics such as NMDA receptor antagonism, neuroplasticity mechanisms, and the metabolite pathways of ketamine. It contains an in-depth analysis of dosing pharmacokinetics, drug interactions, contraindications, and the intricate relationship between ketamine's dissociative and antidepressant properties. For clinicians working with ketamine therapy, this manual serves as a critical desk reference for understanding the sophisticated pharmacological principles underlying this versatile therapeutic agent, making it an essential resource for evidence-based clinical decision-making.

Your Personal Desk Reference Guide

The manual serves as both an educational resource and a detailed pharmacological reference, covering advanced topics such as NMDA receptor antagonism, neuroplasticity mechanisms, and the metabolite pathways of ketamine. It contains an in-depth analysis of dosing pharmacokinetics, drug interactions, contraindications, and the intricate relationship between ketamine’s dissociative and antidepressant properties. For clinicians working with ketamine therapy, this manual serves as a critical desk reference for understanding the sophisticated pharmacological principles underlying this versatile therapeutic agent, making it an essential resource for evidence-based clinical decision-making.

Ketamine Research Institute Clinical Companion App

The Clinical Companion That Transforms Ketamine Care

The Ketamine Research Institute Clinical Companion App is a point-of-care digital tool that transforms the advanced principles of the KRI Mini-Fellowship into practical, bedside support for clinicians. It combines precision dosing calculators based on the Clements 250 PK model with real-time infusion simulation curves, integrating the “5 M’s” of ketamine effectiveness—mass, medications, co-morbidity, metabolism, and mindset—to deliver target-determined infusions personalized to each patient. The app streamlines patient evaluation with selection checklists and contraindication alerts, incorporates genetic and metabolic considerations such as CYP450, MTHFR, and BDNF genetic variants, and provides condition-specific plasma concentration targets for depression, PTSD, anxiety, and chronic pain.

To ensure safety and compliance, it includes built-in documentation templates, logbook tools, and quick reference guides aligned with APA, ASA, and DEA standards. Acting as a digital mentor, safety safeguard, and performance optimizer, the Clinical Companion App empowers clinicians to achieve superior outcomes, reduce risk, and bring the whole precision medicine approach of KRI directly into daily practice.

Ketamine PLUS: The Clinician’s Marketing Handbook

Establishing Professional Excellence and Recognition in Ketamine Therapy.

This comprehensive marketing strategy manual empowers KRI fellowship-trained clinicians to establish themselves as recognized experts in advanced ketamine therapy while ensuring the highest standards of patient care and professional practice. By implementing the evidence-based communication strategies outlined in this guide, you will effectively differentiate your personalized medicine approach from standard protocols, helping patients and referring physicians understand the superior safety profile and clinical outcomes achieved through pharmacokinetic modeling, individualized dosing, and continuous monitoring protocols.

The manual provides ethical frameworks for communicating your advanced training credentials, clinical expertise, and commitment to exceeding APA and ASA recommendations, positioning you as the preferred provider for treatment-resistant patients who require sophisticated medical intervention beyond conventional approaches.

Be Recognized as a Ketamine Expert

The systematic implementation of these professional marketing principles directly supports improved patient outcomes by ensuring that individuals requiring advanced ketamine protocols can identify and access your specialized services. Through targeted educational content, professional networking strategies, and evidence-based messaging, you will build a referral network of healthcare providers who understand when to recommend personalized ketamine therapy over standard treatments, ultimately improving treatment success rates and patient safety in your community.

This approach not only establishes your reputation as a clinical expert committed to the highest standards of care but also ensures that your practice operates in full compliance with professional guidelines while serving patients who have exhausted traditional treatment options and require the sophisticated, individualized protocols that only KRI-trained specialists can provide.

Complete Implementation Package: A 110-page strategy manual featuring evidence-based frameworks, professional communication templates, and systematic approaches for establishing clinical expertise while upholding the highest standards of patient care and professional compliance.

Leading the Future of Precision Ketamine Therapy

Our program and approach are more than training—it’s a transformation.

It offers an unmatched clinical education that distinguishes you as a leader in ketamine therapy. Become the go-to expert in ketamine therapy, trusted by peers and sought out by discerning patients.

The Mini-Fellowship Training Program offers rigorous clinical knowledge, practical skills, and access to a global network of respected professionals. Gain the confidence and credentials to speak at conferences, publish, and mentor others in this rapidly growing specialty. Position yourself as a trusted authority, ready to lead colleagues and patients alike into the new era of medical therapeutics.

Ready to advance your career, expand your impact, and lead in the field of transformative medicine? Join us in the only program that combines personal ketamine experience, hands-on clinical training, and advanced precision medicine techniques in one comprehensive package.

Elevate Your Ketamine Practice with the Knowledge That Makes a Difference

Other ketamine training programs often rely on outdated, unvetted protocols, leading to poor patient outcomes, ineffective treatments, and dissatisfaction. The Mini-Fellowship in Ketamine Therapy will correct these flaws and transform your clinical practice.

Our comprehensive program equips clinicians with:

Advanced Knowledge: Evidence-based techniques to ensure efficacy and safety.
Hands-On Experience: Practical Skills for Real-World Success.
Personal Insights: Firsthand experience with ketamine therapy to enhance patient understanding.
Ongoing Mentorship: A full year of expert guidance to implement and refine your skills.
By addressing common pitfalls and outdated practices, the Mini-Fellowship empowers you to achieve superior patient outcomes, setting a new standard of care. Whether you're starting or refining your practice, this program offers the tools and support needed to succeed.

Transform your practice—join the Mini-Fellowship today.

Our training course offers exclusive small-group private tutorials, meticulously designed to deliver the most immersive and instructive experience. Tailored for clinicians who aspire to develop true expertise and achieve high clinical success rates, this program combines focused, personalized instruction with hands-on learning, ensuring practical skills and deep insights that translate directly into exceptional patient outcomes.

Whether you're just beginning to explore ketamine therapy or have already integrated it into your practice without seeing the transformative results you envisioned, now is the time to acquire the essential knowledge that will revolutionize your approach. By enhancing patient outcomes and ensuring the highest standards of safety, you can profoundly impact those who need it most and position yourself as a leader in innovative mental health treatment.

Our cutting-edge training offers exclusive insights and advanced techniques that most clinicians lack and other programs do not provide. It equips you with the tools to improve patient outcomes and confidently integrate ketamine therapy into your practice safely and successfully. Don't miss the opportunity to elevate your expertise—unlock the potential of ketamine therapy and transform your practice today!

The Ketamine Research Institute: "Mini-Fellowship" Intensive Training Course for Clinicians

A 3-Day Comprehensive Training Program: Elevates Your Expertise in Ketamine Therapy

Our one-year Professional Guidance and Personal Mentoring Program sets it apart.

What Sets Our Program Apart From All Others:

The KRI "Mini-Fellowship" Intensive Training Course is an unparalleled, cutting-edge program designed for clinicians aspiring to specialize in ketamine infusion therapy. Our program is the only one in the U.S. that not only meets but exceeds the rigorous training recommendations set by the American Psychiatric Association and the American Society of Anesthesiologists. What truly sets us apart is our commitment to delivering advanced training in the pharmacokinetics of ketamine therapy, empowering you to provide more effective, safer, and better-tolerated treatments for your patients.

Additionally, we are the only program that offers supervised clinical experience, allowing you to gain hands-on expertise under the guidance of seasoned professionals. We also provide the unique opportunity to personally experience a ketamine infusion. This invaluable experience gives you the insight and knowledge to make more informed decisions when selecting and treating your patients.

Beyond our comprehensive curriculum, we are dedicated to your long-term success. Our graduates benefit from one year of ongoing personalized mentoring and professional consultation, ensuring you are never alone in navigating this rapidly evolving field.

Stand out as an actual "Ketamine Expert" and not just another "Ketamine Clinic"

Our training program is not just a step towards opening a "ketamine clinic" but a comprehensive educational journey that empowers you to become a "true expert" in the field. By choosing our program, you are investing in the advanced skills, knowledge, and professional development necessary to excel in ketamine therapy, setting yourself apart in a crowded marketplace of "ketamine clinics" and ensuring the highest quality care for your patients.

Become one of the Top 100 Ketamine Clinicians

In an era where mental health treatment demands innovation and precision, mastering ketamine therapy through advanced Precision Medicine training represents a transformative step forward for clinicians. Our innovative training methodology arms practitioners with the most advanced precision medicine techniques, essential clinical skills, and "hands-on" experience necessary to become experts in the field of ketamine therapy.

This comprehensive preparation allows them to customize and tailor ketamine treatments with unmatched effectiveness and safety, setting a new standard in patient care. The "Mini-Fellowship" program is more than training; it's a transformational experience that positions you at the vanguard of personalized ketamine therapy.

Transform Lives with Cutting-Edge Ketamine Infusion Therapy 

Are you a Primary Care Physician interested in incorporating ketamine infusion therapy into your practice? Look no further than the Ketamine Research Institute's new "Mini-Fellowship" program. This comprehensive training program provides clinicians with a personalized learning approach and a focus on meeting or exceeding the training standards set by the American Psychiatric Association (APA) and the American Society of Anesthesiologists (ASA).

The KRI Mini-Fellowship Intensive Training Program for Primary Care Physicians

Ketamine infusion therapy is an exciting new development in the world of psychiatry and mental health treatment. It has shown great promise in the treatment of a variety of mental health conditions, including depression, bipolar disorder, anxiety, and post-traumatic stress disorder (PTSD).

As the use of ketamine for treating various medical conditions continues to grow, so does the need for healthcare providers to be properly trained in its administration. However, as with any new treatment modality, it is critically important that clinicians have the proper training necessary to administer ketamine safely and effectively.

The Ketamine Research Institute's  "Mini-Fellowship" intensive training course aims to equip clinicians with the knowledge and skills to administer ketamine infusion therapy safely and effectively.

The program is led by Dr. Gerald W. Grass, a nationally recognized expert in ketamine therapy, who has been instructing physicians, fellows, and government organizations such as the Veterans Administration and the Department of Defense in ketamine therapy since 2010.

Meeting and Exceeding APA and ASA Guidelines for Ketamine Therapy Training

The "Mini-Fellowship" intensive training course is tailored to meet or exceed the recommendations for clinician training in ketamine infusion therapy by leading medical organizations such as the American Psychiatric Association (APA) and the American Society of Anesthesiologists (ASA). This commitment to rigorous standards underscores the institute's dedication to providing the highest level of education and training for clinicians seeking to incorporate ketamine therapy into their practices.

A Comprehensive Educational Experience with Evidence-Based Didactic Lectures and Hands-On Clinical Experiences

The comprehensive educational experience includes evidence-based didactic lectures, interactive discussions, case studies, and hands-on clinical experiences administering ketamine infusions. What sets this program apart from other ketamine infusion training programs is that it takes place at a fully operational ketamine center. In addition, it provides trainees with supervised "hands-on" clinical infusion experience under the guidance of more experienced clinicians, allowing them to experience a ketamine infusion personally.

Personalized Learning and Practical Experience for Building Confidence in Ketamine Infusion Therapy

The training program features a comprehensive didactic curriculum that covers a range of critical topics, including advanced pharmacokinetic dosing strategies and a Precision Medicine approach to patient selection and evaluation. Participants will have ample opportunities to observe and participate in supervised clinical infusion sessions, which provide invaluable hands-on experience and help to build confidence in administering ketamine infusions to patients.

Unique Personal Ketamine Experience for Deeper Understanding of Ketamine Therapy

"Our program is designed to provide clinicians with the most comprehensive and up-to-date training in ketamine infusion therapy," said Dr. Grass. "Our unique personal ketamine experience sets us apart from other programs and provides our trainees with a deeper understanding of the phenomenological aspects of ketamine therapy. This experience also enables clinicians to develop valuable insights into the 'ketamine experience,' which can help them better understand and treat patients receiving this innovative therapy."

Advanced Knowledge and Expertise in Administering Ketamine Infusions Safely and Effectively

Upon completing the "Mini-Fellowship" intensive training course, participants will receive a certificate of completion that attests to their advanced knowledge and expertise in administering ketamine infusions safely and effectively. Trainees will be able to confidently diagnose, treat, and manage a range of psychiatric and chronic pain conditions using ketamine therapy.

Applications Now Open for the "Mini-Fellowship" Intensive Training Course.

Applications for the "Mini-Fellowship" intensive training course are now open. For more information or to apply, interested individuals can visit the Ketamine Research Institute's website at www.ketamineinstitute.com.

The Ketamine Research Institute's "Mini-Fellowship" intensive training course is an excellent opportunity for clinicians seeking to incorporate ketamine therapy into their practices. With its comprehensive curriculum, personalized learning, and practical experience, the program provides participants with the skills and knowledge they need to administer ketamine infusions safely and effectively.

To Learn More About Ketamine Training

The Ketamine Research Institute  is the only training program that offers an intensive, didactic, and experiential "Mini-Fellowship" in ketamine-based therapy. This is not a simple online course, but an opportunity for clinicians to come and spend several days with us in an immersive learning environment - an actual ketamine infusion center. This type of training is certainly more intensive and expensive to provide, but the education, experience, ongoing support, and mentorship you receive are invaluable.

Experienced experts in the field of clinical ketamine research and therapy designed our program. It incorporates the latest advances in our understanding of how ketamine works, as well as new protocols and techniques to enhance ketamine effectiveness in a "real-world" setting that is not available anywhere else in the United States.

What Our Graduates Are Saying

The “Ketamine Infusion Therapy for Mood Disorders” training course for clinicians went above and beyond my expectations. Dr. Grass' brilliance and profound professional expertise made this course an unforgettable and truly eye-opening experience. I can now understand Ketamine from a pharmacological, anesthesiology, psychiatric, medico-legal, and therapeutic perspective. I was able to put the contents I learned immediately into practice and my patients are already profiting from the knowledge I gained.

Ricardo Febres Landauro, MD - Neurologist/Psychiatrist

This is just a token of appreciation for your time and patience. When I enrolled in your program, it was not my intent to participate by exhaustively asking questions, but it became apparent that I had overestimated my fund of knowledge.

Although I have extensive clinical experience with ketamine, and I work at expanding my understanding of the fundamental physiology and pharmacology involved in the administration of ketamine for mental health disorders, I had no idea how much I didn't know.

All the knowledge that I had acquired needed the perspective and clinical understanding that you were willing to share. Thanks again for your help.

Your program exceeded all expectations"

Mark Garwin, MD - Anesthesiologist

"Thank you again for an informative, enlightening, and practical course! Christy and I thoroughly enjoyed our experience with you, and we are excited to get all of our ducks in a row to get started with the ketamine infusions for mood disorders.

We appreciate your offer to send your forms/documents in a pdf as this will give us a great start in providing the right documentation, consent, etc… which interestingly our malpractice carrier is requesting. (I guess PA is not as progressive as FL.)

The course was fantastic….exactly what I was hoping for….evidence-based, scientifically yet practically oriented…allowing us to not only understand the basics of these treatments but some insights as to improve our successes and minimize the “failures” through careful patient selection and optimization.

I am looking forward to applying what we have learned to improve the lives of those in our community who qualify for this treatment and approach! We again thank you for the opportunity and look forward to staying in touch!"

Theresa Burick, MD - Integrative Medicine Specialist

"The course was absolutely helpful! I needed this information to know how to start. Now I know what I need to obtain. However, I may still approach you when I have my first actual patient scheduled later this year and I would love some peer support from you and the others.

I felt I needed the hands-on information to be able to know what my clinic should be like, and now I have a lot of ideas. Also, I needed the scientific approach of how to calculate/know what plasma concentration can work for whom and how to possibly change it. Now I have something better I can work with than the Yale protocol as an IM or trochee dose (never seemed optimal and nobody explains it - yet people do whatever).

As I am not a psychiatrist or anesthesiologist I knew I had to do this training to cover my ass and I am grateful I did. I believe everyone working with Ketamine should experiment with it and other psychedelics. Nevertheless, you have to experience it to be able to serve others appropriately. Thanks for offering access to a personal experience, even for those who would not consider it otherwise."

Rixt Luikenaar, MD - OB/GYN, Transgender Specialist

"The course was Fantastic. Thorough without drawing in details. Fluid and open to conversation. Extremely helpful and exactly what I was looking for! I now have a massive head start in helping the people in my community.

The course surpassed all my expectations. It was all good and encompassing. I think your style which allows for conversation toward what the participants find useful or of interest works really well. And having the day-to-day forms, infusions notes, and protocol/SOP forms are just so exceedingly helpful.

About the "ketamine experience"... for me personally I would like to try it again to get the larger experience! Unfortunately for you, I only trust you to do it.  To see the differences between the way people respond to the experience really brought it home.

It was Excellent!"

Edward Campbell, MD - Anesthesiologist

"I thoroughly enjoyed the course and thought it was a good mix of science and practical knowledge. And of course, it was very helpful as I had no clinical experience with Ketamine and just a little knowledge from what I’ve read...

It gave me a clear road map moving forward. I’m sure there is a lot still to learn, but you never know what you don’t know until it arises....Having access to your forms and waivers, etc. is huge!...

No other training offers an actual infusion for us to experience what it’s like. Having done it now, I can appreciate how difficult it would be to explain it without having done it."

David Smith, MD - Internist/Family Practice