Transform Lives with Cutting-Edge Ketamine Infusion Therapy 

If you’re an MD, DO, NP, or CRNA seeking to revolutionize your practice and establish yourself as an expert in ketamine therapy, look no further. The Ketamine Research Institute’s "Mini-Fellowship" Intensive Training Program is not just another ketamine course—it’s the definitive pathway to clinical excellence, patient satisfaction, and professional recognition in this rapidly evolving field. The Mini-Fellowship Intensive is the most advanced and comprehensive ketamine training available—designed for clinicians serious about mastering precision-based, high-impact therapy.

Unlike online-only courses, this program provides a comprehensive blend of didactic instruction, immersive hands-on clinical experience, and one year of professional mentoring. Clinicians are trained using a cutting-edge approach to Personalized Medicine and Targeted Infusion Therapy, learning not only the fundamentals but also advanced pharmacokinetic modeling, precision dosing, and patient-tailored protocols. This ensures you can deliver safer, more effective, and better-tolerated treatments, setting your practice apart from typical "one-size-fits-all" protocols.

The KRI APA/ASA Compliant "Mini-Fellowship" Training Program for Clinicians

Ketamine infusion therapy is an exciting new development in the world of psychiatry and mental health treatment. It has shown great promise in the treatment of a variety of mental health conditions, including depression, bipolar disorder, anxiety, and post-traumatic stress disorder (PTSD).

As the use of ketamine for treating various medical conditions continues to grow, so does the need for healthcare providers to be properly trained in its administration. However, as with any new treatment modality, it is critically important that clinicians have the proper training necessary to administer ketamine safely and effectively.

The Ketamine Research Institute's "Mini-Fellowship" intensive training course aims to equip clinicians with the knowledge and skills to administer ketamine infusion therapy safely and effectively.

The program is led by Dr. Gerald W. Grass, a nationally recognized expert in ketamine therapy, who has been instructing physicians, fellows, and government organizations, including the Veterans Administration and the Department of Defense, in ketamine therapy since 2013.

Meeting and Exceeding APA and ASA Guidelines for Ketamine Therapy Training

The "Mini-Fellowship" intensive training course is tailored to meet or exceed the recommendations for clinician training in ketamine infusion therapy set forth by leading medical organizations, including the American Psychiatric Association (APA) and the American Society of Anesthesiologists (ASA). This commitment to rigorous standards underscores the institute's dedication to providing the highest level of education and training for clinicians seeking to incorporate ketamine therapy into their practices.

A Comprehensive Educational Experience with Evidence-Based Didactic Lectures and Hands-On Clinical Experiences

The comprehensive educational experience includes evidence-based didactic lectures, interactive discussions, case studies, and hands-on clinical experiences administering ketamine infusions. What sets this program apart from other ketamine infusion training programs is that it takes place at a fully operational ketamine center. In addition, it provides trainees with supervised "hands-on" clinical infusion experience under the guidance of more experienced clinicians, allowing them to experience a ketamine infusion personally.

Unique Personal Ketamine Experience for Deeper Understanding of Ketamine Therapy

"Our program is designed to provide clinicians with the most comprehensive and up-to-date training in ketamine infusion therapy," said Dr. Grass. "Our unique personal ketamine experience sets us apart from other programs and provides our trainees with a deeper understanding of the phenomenological aspects of ketamine therapy. This experience also enables clinicians to develop valuable insights into the 'ketamine experience,' which can help them better understand and treat patients receiving this innovative therapy."

Personalized Learning and Practical Experience for Building Confidence in Ketamine Infusion Therapy

The training program features a comprehensive didactic curriculum that covers a range of critical topics, including advanced pharmacokinetic dosing strategies and a Precision Medicine approach to patient selection and evaluation. Participants will have ample opportunities to observe and participate in supervised clinical infusion sessions, which provide invaluable hands-on experience and help to build confidence in administering ketamine infusions to patients.

Advanced Knowledge and Expertise in Administering Ketamine Infusions Safely and Effectively

Upon completing the "Mini-Fellowship" intensive training course, participants will receive a certificate of completion that attests to their advanced knowledge and expertise in administering ketamine infusions safely and effectively. Trainees will be able to confidently diagnose, treat, and manage a range of psychiatric and chronic pain conditions using ketamine therapy.

Our Invaluable Tools for Success in Ketamine Therapy include:

The Complete Clinical Reference Manual of Ketamine: From Theory to Practice

The Ketamine Research Institute training manual represents a comprehensive compendium of advanced ketamine knowledge, authored by Dr. Gerald W. Grass, MD, Medical Director of KRI. The manual serves as an invaluable reference source, consolidating cutting-edge research, pharmacokinetic principles, and a mechanistic understanding of ketamine's complex therapeutic actions across multiple clinical applications.

Your Desk Companion for Ketamine Therapy

The manual serves as both an educational resource and a detailed pharmacological reference, covering advanced topics such as NMDA receptor antagonism, neuroplasticity mechanisms, and the metabolite pathways of ketamine. It contains an in-depth analysis of dosing pharmacokinetics, drug interactions, contraindications, and the intricate relationship between ketamine's dissociative and antidepressant properties. For clinicians working with ketamine therapy, this manual serves as a critical desk reference for understanding the sophisticated pharmacological principles underlying this versatile therapeutic agent, making it an essential resource for evidence-based clinical decision-making.

Leading the Future of Precision Ketamine Therapy

This program offers exclusive features not found anywhere else, including:

• Enhanced Patient Selection Protocol – Master our proprietary screening methodology that goes beyond basic contraindications to identify ideal candidates, dramatically improving success rates and reducing adverse outcomes
• Pre-Infusion Evaluation and Optimization Program – Learn our systematic patient preparation protocols that optimize treatment readiness through targeted interventions, ensuring maximum therapeutic benefit from each session
• Precision Medicine Protocols – Master genetic-based dosing strategies incorporating MTHFR, BDNF, and CYP450 variations for personalized treatment optimization.
• Hands-On Clinical Training – Perform actual ketamine infusions under expert supervision in our operational clinic, gaining real-world experience impossible to replicate online
• Personal Ketamine Experience – You’ll undergo a supervised ketamine infusion yourself, gaining invaluable firsthand insight into your patients’ journey that transforms your treatment approach and patient selection abilities.
• Target-Controlled Infusion (TCI) Mastery – Learn advanced pharmacokinetic modeling for precise plasma concentration targeting, moving beyond crude weight-based dosing to true precision medicine
• Elite Small Cohorts – A maximum of 4 participants per program ensures personalized, one-to-one mentoring, as opposed to unlimited online enrollment elsewhere.
• Comprehensive Mentorship – One year of individual guidance and mentoring transforms you into a recognized authority on ketamine, not just another provider.
  

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Ketamine Research Institute Clinical Companion App

The Clinical Companion That Transforms Ketamine Care

The Ketamine Research Institute Clinical Companion App is a point-of-care digital tool that transforms the advanced principles of the KRI Mini-Fellowship into practical, bedside support for clinicians. It combines precision dosing calculators based on the Clements 250 PK model with real-time infusion simulation curves, integrating the “5 M’s” of ketamine effectiveness—mass, medications, co-morbidities, metabolism, and mindset—to deliver target-determined infusions personalized to each patient. The app streamlines patient evaluation with selection checklists and contraindication alerts, incorporates genetic and metabolic considerations such as CYP450, BDNF, and MTHFR variants, and provides condition-specific plasma concentration targets for depression, PTSD, anxiety, and chronic pain.

To ensure safety and compliance, it includes built-in documentation templates, logbook tools, and quick reference guides aligned with APA, ASA, and DEA standards. Acting as a digital mentor, safety safeguard, and performance optimizer, the Clinical Companion App empowers clinicians to achieve superior outcomes, reduce risk, and bring the full precision medicine approach of KRI directly into daily practice.

Our program and approach are more than training—it’s a transformation.

It offers an unmatched clinical education that distinguishes you as a leader in ketamine therapy. Become the go-to expert in ketamine therapy, trusted by peers and sought out by discerning patients.

The Mini-Fellowship Training Program offers rigorous clinical knowledge, practical skills, and access to a global network of respected professionals. Gain the confidence and credentials to speak at conferences, publish, and mentor others in this rapidly growing specialty. Position yourself as a trusted authority, ready to lead colleagues and patients alike into the new era of medical therapeutics.

Ready to advance your career, expand your impact, and lead in the field of transformative medicine? Join us in the only program that combines personal ketamine experience, hands-on clinical training, and advanced precision medicine techniques in one comprehensive package.

Applications Now Open for the "Mini-Fellowship" Intensive Training Course.

Applications for the "Mini-Fellowship" intensive training course are now open. For more information or to apply, interested individuals can visit the Ketamine Research Institute's website at www.ketamineinstitute.com.

The Ketamine Research Institute's "Mini-Fellowship" intensive training course is an excellent opportunity for clinicians seeking to incorporate ketamine therapy into their practices. With its comprehensive curriculum, personalized learning, and practical experience, the program provides participants with the skills and knowledge they need to administer ketamine infusions safely and effectively.

To Learn More About Ketamine Training

The Ketamine Research Institute  is the only training program that offers an intensive, didactic, and experiential "Mini-Fellowship" in ketamine-based therapy. This is not a simple online course, but an opportunity for clinicians to come and spend several days with us in an immersive learning environment - an actual ketamine infusion center. This type of training is certainly more intensive and expensive to provide, but the education, experience, ongoing support, and mentorship you receive are invaluable.

Our program was designed by experienced experts in the field of clinical ketamine research and therapy. It incorporates the latest advances in our understanding of how ketamine works, as well as new protocols and techniques to enhance ketamine effectiveness in a "real-world" setting that is not available anywhere else in the United States.

What Our Graduates Are Saying

The “Ketamine Infusion Therapy for Mood Disorders” training course for clinicians went above and beyond my expectations. Dr. Grass' brilliance and profound professional expertise made this course an unforgettable and truly eye-opening experience. I can now understand Ketamine from a pharmacological, anesthesiology, psychiatric, medico-legal, and therapeutic perspective. I was able to put the contents I learned immediately into practice and my patients are already profiting from the knowledge I gained.

Ricardo Febres Landauro, MD - Neurologist/Psychiatrist

This is just a token of appreciation for your time and patience. When I enrolled in your program, it was not my intent to participate by exhaustively asking questions, but it became apparent that I had overestimated my fund of knowledge.

Although I have extensive clinical experience with ketamine, and I work at expanding my understanding of the fundamental physiology and pharmacology involved in the administration of ketamine for mental health disorders, I had no idea how much I didn't know.

All the knowledge that I had acquired needed the perspective and clinical understanding that you were willing to share. Thanks again for your help.

Your program exceeded all expectations"

Mark Garwin, MD - Anesthesiologist

"Thank you again for an informative, enlightening, and practical course! Christy and I thoroughly enjoyed our experience with you, and we are excited to get all of our ducks in a row to get started with the ketamine infusions for mood disorders.

We appreciate your offer to send your forms/documents in a pdf as this will give us a great start in providing the right documentation, consent, etc… which interestingly our malpractice carrier is requesting. (I guess PA is not as progressive as FL.)

The course was fantastic….exactly what I was hoping for….evidence-based, scientifically yet practically oriented…allowing us to not only understand the basics of these treatments but some insights as to improve our successes and minimize the “failures” through careful patient selection and optimization.

I am looking forward to applying what we have learned to improve the lives of those in our community who qualify for this treatment and approach! We again thank you for the opportunity and look forward to staying in touch!"

Theresa Burick, MD - Integrative Medicine Specialist

"The course was absolutely helpful! I needed this information to know how to start. Now I know what I need to obtain. However, I may still approach you when I have my first actual patient scheduled later this year and I would love some peer support from you and the others.

I felt I needed the hands-on information to be able to know what my clinic should be like, and now I have a lot of ideas. Also, I needed the scientific approach of how to calculate/know what plasma concentration can work for whom and how to possibly change it. Now I have something better I can work with than the Yale protocol as an IM or trochee dose (never seemed optimal and nobody explains it - yet people do whatever).

As I am not a psychiatrist or anesthesiologist I knew I had to do this training to cover my ass and I am grateful I did. I believe everyone working with Ketamine should experiment with it and other psychedelics. Nevertheless, you have to experience it to be able to serve others appropriately. Thanks for offering access to a personal experience, even for those who would not consider it otherwise."

Rixt Luikenaar, MD - OB/GYN, Transgender Specialist

"The course was Fantastic. Thorough without drawing in details. Fluid and open to conversation. Extremely helpful and exactly what I was looking for! I now have a massive head start in helping the people in my community.

The course surpassed all my expectations. It was all good and encompassing. I think your style which allows for conversation toward what the participants find useful or of interest works really well. And having the day-to-day forms, infusions notes, and protocol/SOP forms are just so exceedingly helpful.

About the "ketamine experience"... for me personally I would like to try it again to get the larger experience! Unfortunately for you, I only trust you to do it.  To see the differences between the way people respond to the experience really brought it home.

It was Excellent!"

Edward Campbell, MD - Anesthesiologist

"I thoroughly enjoyed the course and thought it was a good mix of science and practical knowledge. And of course, it was very helpful as I had no clinical experience with Ketamine and just a little knowledge from what I’ve read...

It gave me a clear road map moving forward. I’m sure there is a lot still to learn, but you never know what you don’t know until it arises....Having access to your forms and waivers, etc. is huge!...

No other training offers an actual infusion for us to experience what it’s like. Having done it now, I can appreciate how difficult it would be to explain it without having done it."

David Smith, MD - Internist/Family Practice